Seroprevalence of SARS-CoV-2 in southwest Goiás, Brazil, 2020: a population-based cross-sectional serological study

Abstract

Aim:The COVID-19 pandemic has been causing significant socioeconomic and health implications worldwide. We aimed to perform a population-based serological survey of SARS-CoV-2 in Quirinópolis, Goiás and to relate the infection to sociodemographic and epidemiological aspects.Methods: Systematic sampling and active search in the community was conducted using a rapid detection kit for specific IgG and IgM. Three collection phases occurred between September and October 2020.Results: In total, 557 volunteers participated in the study. The general seroprevalence rate was 8.1%, with one-off prevalence of 10.4%, 6.7% and 6.8% in each of the three phases. There was a predominance of results for IgG antibodies (88.9%). The bivariate analysis revealed that age < 19 years (OR = 5.0; 95%CI: 2.10-11.90; P = 0.0003), search for medical care (OR = 2.21; 95%CI: 1.10-4.31; P = 0.03), families of 3-4 residents (OR = 2.34; 95%CI: 1.08-5.05; P = 0.03) and the presence of symptoms (OR = 3.59; 95%CI: 1.92-6.78; P < 0.001) were associated with antibody detection. The symptoms related to the detection of antibodies were mainly fever