Seroprevalence of Toxoplasma gondii among ocular infection patient in Shahid Dr. Aso Hospital in Sulaimani City, Iraq

Abstract

Toxoplasma gondii is an intracellular protozoan parasite that causes ocular toxoplasmosis with most complications such as developing eye lesions and impaired vision. During the period from October 2021 to April 2022, a total of 174 blood samples were taken from ocular infected patients whom visited Shahid Dr. Aso Hospital in Sulaimani City, Iraq. These samples were tested serologically for detection of anti-Toxoplasma gondii antibodies (IgG and IgM) with both imunochromatograhpy (rapid test) and ELISA. The serological test demonstrated that 63 IgG (36.2%) and 4 IgM (2.2%) were positive by rapid test imunochromatograhpy. While, 80 IgG (45.9%) and 2 IgM (1.1%) were positive by ELISA. Most of the infections (58.75%) were between 50-69 years old. All patients (80) were examined for intraocular toxoplasmosis lesion, only 10 patients (12.5%) including 2 males (2.5%) and 8 females (10%) had ocular toxoplasmosis lesions. Most of the lesions were scars (old type) while, in some patients they were active lesions. The types of lesions, numbers per each eye, lesion diameter and comparison with the IgG and IgM titers were demonstrated.

Biomarker Evaluation in Toxoplasma gondii-infected Patients

“…not recorded any mixed IgM+IgG in any samples.show a table (1). The results of the current study agreed with the results of both [13] in Sulaymaniyah, [14] in Salah al -Din, [15] in Tikrit, The researchers observed a higher prevalence of IgG antibodies in pateints compared to the prevalence of IgM antibodies. While the results of the current study did not concur with the [16] in the northern Tarmiyah district of Baghdad, the percentage of IgM was higher than the percentage of IgG antibodies in pregnant women.…”