Seroprevalence of toxoplasmosis and rubella in pregnant women attending antenatal private clinic at Ouagadougou, Burkina Faso

Linguissi, Laure Stella Ghoma; Nagalo, Bolni Marius; Bisseyé, Cyrille; Kagoné, Thérèse; Sanou, Mahamoudou; Tao, Issoufou; Benao, Victoire; Simporé, Jacques; Koné, B

doi:10.1016/s1995-7645(12)60148-5

Cited by 42 publications

(45 citation statements)

References 14 publications

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“…Our data on seroprevalence of Toxoplasma IgG are in line with another recent study that showed a prevalence rate of 88.7% in pregnant women in Accra [23]. In contrast, a significantly lower rate of 20.3% was determined in Burkina Faso [24]. Whether this discrepancy is based on different test systems applied or different environmental burden with parasites remains to be clarified.…”

Section: Discussionsupporting

confidence: 88%

Prevalence of pregnancy-relevant infections in a rural setting of Ghana

Völker

Cooper²,

Bader

et al. 2017

BMC Pregnancy Childbirth

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BackgroundAlthough infectious diseases still account for a high burden of morbidity and mortality in sub-Saharan Africa, simultaneous investigations on multiple infections affecting maternal and child health are missing.MethodsWe conducted a cross-sectional, single-centre pilot study in a rural area of Ghana to assess the infectiological profile during pregnancy. Screening of 180 expectant mothers was done by vaginal swabs and serology to detect the most common pregnancy-relevant infections. They were also interviewed for potential risk factors, outcome of previous pregnancies, and socio-economic aspects.ResultsWe found a high prevalence of infections caused by hepatitis B virus (16.7% HBs antigen positive). In contrast, infections caused by hepatitis C virus (1.1% anti-HCV) and HIV (0.6%) were rare. Maternal malaria was frequent (10.6%), despite increasing acceptance of intermittent preventive treatment during pregnancy (IPTp). Group B streptococci were present in 10.6% of all pregnant women. Absence of antibodies against varicella zoster virus in 43.2%, Toxoplasma gondii in 26.8%, parvovirus B19 in 20.0%, and rubella virus in 15.7% makes a significant proportion of pregnant women susceptible for acquiring primary infections. Whereas all study participants had specific IgG antibodies against human cytomegalovirus, infections with Listeria, Brucella, or Neisseria gonorrhoeae as well as active syphilis were absent.ConclusionsOur pilot study in a rural community in Ghana indicates an urgent need for action in dealing at least with high-prevalent pregnancy-relevant infections, such as hepatitis B, malaria and those caused by group B streptococci. In addition, the resulting prevalence rates of various other infections may offer guidance for health officials to prioritize possible future intervention schemes.Electronic supplementary materialThe online version of this article (doi:10.1186/s12884-017-1351-3) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 88%

Prevalence of pregnancy-relevant infections in a rural setting of Ghana

Völker

Cooper²,

Bader

et al. 2017

BMC Pregnancy Childbirth

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“…A lower prevalence rate was reported from Benin (30.0 %) (De Paschale et al 2014) and Burkina Faso (20.3 %) (Linguissi et al 2012). …”

Section: Western Africamentioning

confidence: 69%

Sero-epidemiology and risk factors for Toxoplasma gondii among pregnant women in Arab and African countries

Alsammani

2014

J Parasit Dis

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The epidemiology of toxoplasmosis in pregnancy is a major issue for public health. Primary infection in pregnant women can lead to serious sequelae. This review examined current sero-epidemiology and risks factor data for Toxoplasma gondii in pregnant women in Arab and African countries. A systematic electronic search of published literature was conducted. Data were extracted from relevant studies. Seropositivity is high in both regions. African countries have higher seropositivity than Arab countries due to differences in risk factors. Data on T. gondii infection in pregnancy are scant in many countries, especially where there is lack of political stability. Identified risk factors included eating raw meat, proximity with cats, undercooked food, and increasing maternal age. Toxoplasmosis in pregnancy in Arab and African countries is an underestimated health problem. Further research is needed. This report is a foundation for strategies and policies for intervention needed to combat the consequences of congenital toxoplasmosis.

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“…Hamilelikte primer toxoplasmosis geliştiğinde şiddetli patolojik defektlere (düşük, ölü doğum, fetal anomali; hidrosefali, koryoretinit vb) yol açabilen konjenital toksoplazmoz gelişebilmektedir (2,(5)(6)(7)(8). Dünyada gebelerde yapılan çalışmalarda T.gondii IgG antikor seroprevalansının %20,3 ile %79,8 arasında değiştiği görülmektedir (6,7,(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Bu farklılık, bölgesel risk faktörlerinin çeşitlilik göstermesinden kaynaklanmaktadır.…”

Section: Introductionunclassified