Serosurvey of Anti-Toxocara Antibodies and Risk Factors in Relation to Vitamin D Levels Among Pregnant Women of Duhok City –Kurdistan Region

Murad, Manal Adil; EASSA, SOUZAN HUSSAIN; Ibrahim, Shereen

doi:10.31386/dmj.2021.15.2.5

Cited by 4 publications

(2 citation statements)

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“…In brief, the systematic search identified 5190 potentially relevant articles. After removing duplicates and/or noneligible papers, 11 articles from six countries across four continents met the inclusion criteria in the systematic review and meta-analysis [19][20][21][22][23][24][25][26][27][28][29]. Serum samples were evaluated by serology methods for Toxocara.…”

Section: Resultsmentioning

confidence: 99%

Seroprevalence of Toxocara spp. in Pregnant Women: A Systematic Review and Meta-Analysis

Shayanfar,

Bahadory,

Taghipour

et al. 2024

Infectious Diseases in Obstetrics and Gynecology

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Background. Toxocariasis is an important health problem caused by the parasitic species Toxocara canis (T. canis) and Toxocara cati (T. cati). Prevalence of toxocariasis in pregnant women as a vulnerable population is doubly important, and the aim of this study is to estimate the overall prevalence of toxocariasis infection in pregnant women according to the available reports. Methods. The present study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) checklists. A systematic search was carried out in international scientific databases (Google Scholar, Web of Science, ScienceDirect, Scopus, and PubMed) between 1990 and 2023. The overall prevalence of parasitic infection was estimated with a random-effects model. All analyses (overall prevalence, heterogeneity, publication bias, and sensitivity analysis) were performed with comprehensive meta-analysis (V2.2, Bio stat) software. Results. Amid the final eleven included studies, based on the random-effects model, the estimation of the pooled prevalence of Toxocara spp. was 20.8% (95% CI, 9.8–38.7%). The association between the risk factors of toxocariasis and the prevalence of the disease was not statistically significant. Conclusions. In the present study, significant prevalence was reported; however, considering the limited number of studies, it seems that the actual prevalence of the disease is higher. Therefore, it seems necessary to monitor this health problem in pregnant women.

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Section: Resultsmentioning

confidence: 99%

Seroprevalence of Toxocara spp. in Pregnant Women: A Systematic Review and Meta-Analysis

Shayanfar,

Bahadory,

Taghipour

et al. 2024

Infectious Diseases in Obstetrics and Gynecology

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“…All separated serum samples were poured into sterile 2 mL Eppendorf tubes; each tube was labeled, named, and stored at -20°C until use. 25…”

Section: Methodsmentioning

confidence: 99%

Detection of Toxoplasmosis in Association with Autoimmune Thyroid Disease During Pregnancy in Duhok, Iraq

Murad¹,

Eassa²

2023

J. Pure Appl. Microbiol.

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Toxoplasma gondii is a protozoan parasite that is widely distributed in the human population and is responsible for corresponding global morbidity. Specifically, T. gondii causes toxoplasmosis, leading to miscarriage, stillbirth, and neural disorders. This parasite attacks different human organs and glands, such as the thyroid gland, and causes various corresponding health issues. Recently, studies have established a link between T. gondii and autoimmune thyroid diseases (AITD), which contributes to preterm delivery, miscarriage, low birth weight, and death. Therefore, the aim of this study was to detect the prevalence of toxoplasmosis and its association with AITD among pregnant women. A total of 180 blood samples were collected from pregnant women and examined using an enzyme-linked immunosorbent assay (ELISA). The patients were within the age range of 15–50 years old, and lived in Duhok City, Iraq; samples and clinical information was collected from August 2021 to February 2022. The corresponding blood samples were tested for anti-Toxoplasma IgG antibody, Toxoplasma IgG avidity, FT3, FT4, and TSH hormones, and TPO, Tg, and TSHR antibodies. Overall, our results showed that out of 180 pregnant women, 110 (61.1%) were seropositive for anti-Toxoplasma IgG antibody; specifically, 25 (22.7%) and 85 (77.3%) had recent and past infections, respectively. Approximately 54.4% (98) of the pregnant women had thyroid disorders; further, 22 (12.2%), 13 (7.2%), and 8 (4.4%) women had TPO, Tg, and TSHR antibodies, respectively. A total of 43 (23.8%) patients screened positive for AITD. Out of the 110 Toxoplasma IgG–positive women, 35 (31.8%) had AITD. The older women, rural residents, restaurant food consumers, and women with cat contact had relatively high infection rates. Toxoplasma seropositive women had more elevated autoantibodies than seronegative ones. In conclusion, this study demonstrated a high rate of toxoplasmosis and a corresponding association with thyroid hormones changes and AITD in pregnant women in Duhok, Iraq. Further, it is necessary to reduce overall infection rates through effective health and educational programs. Therefore, it is essential to measure Toxoplasma antibodies, screen for thyroid hormones and autoantibodies, and encourage gynecologist visits to reduce the risks to mothers and fetuses.

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Distribution and risk factors of Trichomonas vaginalis infection with relevance to interleukin profile among population in Duhok city, Iraq

Adil Murad,

Ibrahim,

Mahmood

2024

Clinical Epidemiology and Global Health

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Serosurvey of Anti-Toxocara Antibodies and Risk Factors in Relation to Vitamin D Levels Among Pregnant Women of Duhok City –Kurdistan Region

Cited by 4 publications

References 0 publications

Seroprevalence of Toxocara spp. in Pregnant Women: A Systematic Review and Meta-Analysis

Seroprevalence of Toxocara spp. in Pregnant Women: A Systematic Review and Meta-Analysis

Detection of Toxoplasmosis in Association with Autoimmune Thyroid Disease During Pregnancy in Duhok, Iraq

Distribution and risk factors of Trichomonas vaginalis infection with relevance to interleukin profile among population in Duhok city, Iraq

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