Serosurvey of anti-Toxoplasma gondii antibodies in homeless persons of São Paulo city, southeastern Brazil

Felipetto, Laís Giuliani; Teider-Junior, Pedro Irineu; Silva, Felipe Fortino Verdan da; Yamakawa, Ana Carolina; Kmetiuk, Louise Bach; Couto, Anahi Chechia do; Martins, Camila Marinelli; Vaz, Eduarda Stankiwich; Ullmann, Leila Sabrina; Langoni, Hélio; Timenetsky, Jorge; Santos, Andrea Pires dos; Biondo, Alexander Welker

doi:10.21203/rs.2.22570/v2

Cited by 2 publications

(2 citation statements)

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“…In such scenarios, wild boars, hunting dogs, and hunters have been surveyed in Brazil for vector-borne, waterborne, and foodborne diseases, for the first time worldwide (21). Moreover, One Health research and outreach community projects with community leaders toward Brazilian social classes vulnerability have provided interesting results in animal hoarders, homeless, incarcerated, indigenous, slum, low-income, and traditional island populations in their environments (22)(23)(24)(25). In such a hands-on approach, companion and livestock animals have been concomitantly surveyed along with their owners, reaching holistic results, and establishing new roles in pathogen cycles of urban and anthropized settings.…”

Section: One Health In Brazilmentioning

confidence: 99%

From the Approach to the Concept: One Health in Latin America-Experiences and Perspectives in Brazil, Chile, and Colombia

Pettan-Brewer

Martins

Abreu

et al. 2021

Front. Public Health

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Professionals throughout the world have been working to assess the interdisciplinary interaction and interdependence between health and wellbeing in a constantly changing environment. The One Health concept was developed to encourage sustainable collaborative partnerships and to promote optimal health for people, animals, plants, the environment, and the whole planet. The dissemination of scientific discoveries and policies, by working directly with diverse communities, has been one of the main goals for Global One Health. The One Health concept has also been referred or related to as “One Medicine, One Medicine-One Health, One World-One Health, EcoHealth,” and Planetary Health,” depending on each fundamental view and approach. In Latin America, despite the concept still being discussed among health professionals and educators, several One Health initiatives have been used daily for more than decades. One Health action has been applied especially in rural and underserved urban areas where low socioeconomic status, lack of health professionals, and scarcity of medical resources may require professionals to work together. Local communities from diverse social and economic statuses, including indigenous populations have been working with institutions and social organizations for many years, accomplishing results through grassroots movements. These “bottom-up” socio-community approaches have also been tools for the prevention and control of diseases, such practice has preceded the One Health concepts in Latin American countries. It is strongly believed that collaborative, multidisciplinary, political, and economic initiatives with prosocial focus may become investments toward obtaining significant results in the face of global, economic and health challenges; working for a healthier world with inclusivity, equity, and equality. In this study, it is briefly presented how the One Health approach has been initiated and developed in Latin America, highlighting the events and actions taken in Brazil, Chile, and Colombia.

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Section: One Health In Brazilmentioning

confidence: 99%

From the Approach to the Concept: One Health in Latin America-Experiences and Perspectives in Brazil, Chile, and Colombia

Pettan-Brewer

Martins

Abreu

et al. 2021

Front. Public Health

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“…The authors are thankful to Dr. Mara Lúcia Gravinatti and the Social Center Our Lady of Good Delivery for helping with collection, sampling, and follow-up information. This manuscript has been released as a pre-print at Research Square (59).…”

Section: Data Availability Statementmentioning

confidence: 99%

Serosurvey of Anti-Toxoplasma gondii Antibodies in Homeless Persons of São Paulo City, Southeastern Brazil

Felipetto

Teider-Junior

Silva

et al. 2020

Front. Public Health

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Seroprevalence of Toxoplasma gondii has been extensively studied in a variety of different human populations. However, no study has focused on homeless populations. Accordingly, the present study aimed to assess the seroprevalence of anti-T. gondii antibodies and the risk factors associated in homeless persons from homeless shelter of São Paulo city, southeastern Brazil. In addition, anti-HIV antibodies and associated risk of T. gondii and HIV coinfection have been evaluated. Anti-T. gondii antibodies were detected by indirect fluorescent antibody test. In addition, anti-HIV levels were tested by chemiluminescence enzyme immunoassay, with positive samples confirmed by rapid immunoblot assay. Overall, IgG anti-T. gondii seropositivity was found in 43/120 (35.8%) homeless persons, with endpoint titers varying from 16 to 1,024. The only two pregnant women tested were negative for IgM by chemiluminescence enzyme immunoassay, with normal parturition and clinically healthy newborns in both cases. There were no statistical differences in the risk factors for anti-T. gondii serology (p > 0.05). Anti-HIV seropositivity was found in 2/120 (1.7%) homeless persons, confirmed as HIV-1. One HIV seropositive individual was also sero-reactive to IgG anti-T. gondii, and both were negative to IgM anti-T. gondii. This is the first study that reports the serosurvey of T. gondii in homeless persons worldwide. Despite the limited sample size available in the present study, our findings have shown that the prevalence of anti-T. gondii antibodies in homeless persons herein was lower than the general population, probably due to homeless diet habit of eating mainly processed food intake. No statistical differences were found regarding risk factors for anti-T. gondii exposure in homeless persons. Future studies should be conducted to fully establish risk factors for anti-T. gondii exposure in homeless persons.

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Serosurvey of anti-Toxoplasma gondii antibodies in homeless persons of São Paulo city, southeastern Brazil

Cited by 2 publications

References 40 publications

From the Approach to the Concept: One Health in Latin America-Experiences and Perspectives in Brazil, Chile, and Colombia

From the Approach to the Concept: One Health in Latin America-Experiences and Perspectives in Brazil, Chile, and Colombia

Serosurvey of Anti-Toxoplasma gondii Antibodies in Homeless Persons of São Paulo City, Southeastern Brazil

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