Serous macular detachments associated with topical travoprost

Abstract

Here is presented a unique case of bilateral serous macular detachments as a side effect of topical travoprost (0.004%) therapy. Only three other cases in the literature have definitively associated this side effect with other topical prostaglandins. The aetiological and pathophysiological pathways remain to be clearly elucidated but are potentially related to increased choroidal vascular permeability. In this case, the subretinal fluid resolved rapidly and completely after cessation of travoprost drops, showing it to be a reversible pathology similar to prostaglandin-associated cystoid macular oedema. This uncommon association is therefore important to consider in the differential diagnosis of serous macular detachment. Increasing ophthalmic awareness could help to prevent unnecessary investigations in undifferentiated patients without other guiding historical or examination features. This may save time and expense for the patient and health systems.

The Effect of Latanoprost on Choroidal Vascularity Index in Glaucoma and Ocular Hypertension

“…Tufan and Gencer32 reported CME in a unilateral glaucoma patient 1 month after starting treatment with topical latanoprost. In the literature, there are numerous reports of phakic cases without risk factors that develop CSCR and CME after PGA use 33–35. However, choroidal imaging was not performed in any of these reported cases.…”

“…In the literature, there are numerous reports of phakic cases without risk factors that develop CSCR and CME after PGA use. [33][34][35] However, choroidal imaging was not performed in any of these reported cases.…”