Serous Microcystic Adenoma to Adenocarcinoma of Pancreas—A Case Report

Prasad, Hari; Ballal, Rajesh; Upadhyaya, Vidya; Makannavar, J H; Shetty, K Jayaprakash; Prakash, Hariprasath

doi:10.1007/s13193-013-0217-z

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Relevant studies have reported that only 1 to 3% of SCNs have been transformed into serous cystadenocarcinomas [3]. To date, only 25–30 serous cystadenocarcinomas have been reported worldwide [4]. Therefore, SCNs are generally considered benign and can be followed up [5].…”

Section: Introductionmentioning

confidence: 99%

A prospective study on endoscopic ultrasound for the differential diagnosis of serous cystic neoplasms and mucinous cystic neoplasms

et al. 2019

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Background To provide criteria for the differential diagnosis of serous cystic neoplasms (SCNs) and mucinous cystic neoplasms (MCNs) by analyzing the imaging features of these two neoplasms by endoscopic ultrasound (EUS). Methods From April 2015 to December 2017, a total of 69 patients were enrolled in this study. All patients were confirmed to have MCNs (31 patients) or SCNs (38 patients) by surgical pathology. All patients underwent EUS examination. The observation and recorded items were size, location, shape, cystic wall thickness, number of septa, and solid components. Results Head/neck location, lobulated shape, thin wall and > 2 septa were the specific imaging features for the diagnosis of SCNs. When any two imaging features were combined, we achieved the highest area under the curve (Az) (0.824), as well as the appropriate sensitivity (84.2%), specificity (80.6%), positive predictive value (PPV) (84.2%), and negative predictive value (NPV) (80.6%). Body/tail location, round shape, thick wall and 0–2 septa were the specific imaging features for the diagnosis of MCNs. When any three imaging features were combined, we obtained the highest Az value (0.808), as well as the appropriate sensitivity (77.4%), specificity (84.2%), PPV (80.0%) and NPV (82.1%). Conclusions Pancreatic cystadenomas that meet any two of the four imaging features of head/neck location, lobulated shape, thin wall and > 2 septa could be diagnosed as SCNs, and those that meet any three of the four imaging features of body/tail location, round shape, thick wall and 0–2 septa could be considered as MCNs. Trial registration The study was registered at the Chinese Clinical Trial Registry. The registration identification number is ChiCTR-OOC-15006118 . The date of registration is 2015-03-20.

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Section: Introductionmentioning

confidence: 99%