Serratia A Novel Source of Secondary Metabolites

AL-Ghanem, Mai Mohammed

doi:10.19080/aibm.2018.11.555814

Cited by 9 publications

(5 citation statements)

References 53 publications

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“…Nonetheless, this is the first time an endophytic Serratia marcescens has been identified from the plant Bryophyllum pinnatum. Authors [10] reported the antibacterial activity of Serratia marcescens metabolites on Staphylococcus aureus and Klebsiella pneumoniae. This could result from the biosynthesis of prodigiosin, an antimicrobial compound Serratia produces.…”

Section: Resultsmentioning

confidence: 99%

Effect of Endophytic Serratia marcescens Isolated from Bryophyllum pinnatum against Clinical Bacterial Isolates

Idris,

Adetunji

2024

PoS

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The world's health is being threatened by antimicrobial resistance (AMR). According to the World Health Organization, it is one of humanity's top ten worldwide public health problems. Serratia marcescens is an opportunistic pathogen that can be isolated from soil, plants, water, and air. Additionally, Serratia species offer a valuable supply of secondary metabolites that are comparatively underutilised and may have anti-MDR pathogenic properties. The present research aimed to determine the antibacterial potential of Serratia marcescens isolated from the leaves of Bryophyllum pinnatum against clinical bacterial isolates. The leaves of Bryophyllum pinnatum were collected, surface sterilised, cultured at 37 °C for 24 hours and identified utilising viteks 2 automated techniques and molecular methods. The crude metabolites extract of Serratia marcescens were extracted and utilised for antibacterial susceptibility testing using agar healthy diffusion methods. The data were measured in the diameter zone of inhibition. This study revealed six endophytic bacteria were isolated from Bryophyllum pinnatum following standard microbiological culture methods. The endophytic bacteria isolate tag L03 was found to be Gram-Negative Rod. The isolate was tentatively identified as Serratia ficaria and molecularly identified as Serratia marcescens. The metabolites of Serratia marcescens endophytes revealed a significant antibacterial activity on Klebsiella pneumoniae with a diameter zone of inhibition of 17.7 mm at 100% concentration, followed by Staphylococcus sciuri with a 12.7 mm diameter zone of inhibition. These results suggested that endophytic bacteria Serratia marcescens were isolated from the leaves of Bryophyllum pinnatum and had shown potent antibacterial activity that could be employed to create new antibacterial agents.

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Section: Resultsmentioning

confidence: 99%

Effect of Endophytic Serratia marcescens Isolated from Bryophyllum pinnatum against Clinical Bacterial Isolates

Idris,

Adetunji

2024

PoS

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“…C. freundii occurs mostly in water, food, soil and sewage. The organism is also associated with non-potable water that normally undergo poor chlorination process ( 31 ).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the physicochemical properties and bacterial loads of selected rivers in Ondo State, Nigeria

Bello,

Akinpeloye,

Bello

et al. 2023

IJM

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Background and Objectives: Water is crucial to human existence but may be contaminated with microorganisms, thus making it unfit for consumption. This study aimed to evaluate the physicochemical properties and bacterial loads of selected river waters in Ondo State, Nigeria. Materials and Methods: Ten major rivers were sampled between April and August, 2021. The pH, temperature, total al- kalinity, colour, turbidity, electrical conductivity, dissolved oxygen, ammonium, aluminium, organic matters, nitrate levels including the microbial loads were determined according to standard procedures. Confirmation of identified isolates was achieved by API 20E and API 20NE. Results: The turbidity, colour, conductivity, ammonium, and aluminium ranged from 4.3 to 15.2 NTU, 4 to 20 NTU, 123.5 to 580.2 mgL-1, 0 to 3.5 mgL-1, and 0.05 to 1.7, respectively. Most physicochemical parameters showed no significant differences from the WHO permissible limits for drinking water (p > 0.05). The total viable bacterial count in the rivers ranged from 1.5 × 105 to 6.3 × 105 CFUmL-1, while the total coliform count ranged from 1.3 × 103 to 4.8 × 103 CFUmL-1. The predominant bacteria were Escherichia coli and Pseudomonas aeruginosa. Conclusion: This study revealed that the physiochemical properties of the waters were majorly within the WHO permissible standards but with significantly higher bacterial loads.

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“…Furthermore, because the Serratia and Burkholderia genera are considered a reservoir of novel secondary metabolites with potent activities, they have become attractive in agriculture. Some of these secondary metabolites have been characterized as antibacterial, antifungal, nematicide, anticoagulant and anti‐inflammatory (AL‐Ghanem, 2018; Elshafie & Camele, 2021; Hellberg et al, 2015; Liu et al, 2010; Petersen & Tisa, 2013; Soenens & Imperial, 2020).…”

Section: Discussionmentioning

confidence: 99%

Cold-adapted strains as plant growth-promoting bacteria on soybean seeds and biocontrol agents against Macrophomina phaseolina

Sarli

Gomes

Reznikov³

et al. 2022

Journal of Applied Microbiology

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Aim:The aim was to characterize cold-adapted bacteria by testing their PGP features and antagonistic activity against Macrophomina phaseolina, both in vitro and coating soybean seeds (Glycine max [L.] Merr.). Methods and results:Burkholderia gladioli MB39, Serratia proteamaculans 136 and Serratia proteamaculans 137 were evaluated. In vitro tests showed that S. proteamaculans 136 and 137 produce siderophore and indole-acetic acid (IAA), solubilize phosphate and fix nitrogen. Additionally, B. gladioli MB39 and S. proteamaculans 137 showed hydrolase activity and potent antifungal effects. The biocontrol efficacy over soybean seeds was evaluated using in vitro and greenhouse methods by immersing seeds into each bacterial suspension. As a result, S. proteamaculans 136 has improved the performance in all the seed germination evaluated parameters. In addition, S. proteamaculans 137 and B. gladioli MB39 strongly inhibited M. phaseolina, reducing the infection index values to 10% and 0%, respectively. Conclusion: Serratia proteamaculans 136, 137 and Burkholderia gladioli MB39 showed plant growth promotion features and inhibition of Macrophomina phaseolina infection by producing different antifungal compounds.Significance and impact of the study: Our results reinforce the application of cold-adapted Serratia proteamaculans and Burkholderia gladioli bacterial strains as candidates for developing microbial formulation to promote plant growth and guarantee antifungal protection in soybean crops.

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Serratia A Novel Source of Secondary Metabolites

Cited by 9 publications

References 53 publications

Effect of Endophytic Serratia marcescens Isolated from Bryophyllum pinnatum against Clinical Bacterial Isolates

Effect of Endophytic Serratia marcescens Isolated from Bryophyllum pinnatum against Clinical Bacterial Isolates

Evaluation of the physicochemical properties and bacterial loads of selected rivers in Ondo State, Nigeria

Cold-adapted strains as plant growth-promoting bacteria on soybean seeds and biocontrol agents against Macrophomina phaseolina

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