Serratia marcescens endophthalmitis secondary to pneumonia

Abstract

Certain associations such as between cylindromas and apocrine cystadenoma are expected, as they are sweat gland proliferations. Similarly, basal cell and squamous cell carcinomas are malignant proliferations of keratinocytes and have similar histogenesis. However, most collision tumours occur by chance, and are not derived from similar cell lines nor share pathogenic mechanisms.The coexistence of two or more neoplasms in a single cutaneous specimen is unusual and can be diagnostically misleading if only one of the two is discovered. Biopsy reports must always be questioned in the light of the clinical history and examination. Unless histopathological diagnoses are considered alongside the clinical appearance of the original lesion, which may be altered by surgery, the anomaly may not be questioned.It is essential therefore that new lesions be photographically documented prior to any intervention. This will aid in the patient's future management particularly in situations where the patient is reviewed by a different clinician at subsequent visits. This objective tool is especially important in cases where the clinical appearance does not correlate well with histological findings. Performing a large incisional biopsy will also maximize the chance of identifying multiple lesions.

Supposed endogenous endophthalmitis caused by <i>Serratia marcescens</i> in a cat

“…There are only a few descriptions of S. marcescens infection in cats, and no ocular or lung involvement has been reported in any (Hohenhaus et al , 1997; Kelly et al , 2015). In humans, S. marcescens is a rare cause of endogenous endophthalmitis, mainly observed in patients with systemic illness, recent non-ocular surgery, indwelling catheters, and immunocompromised status, or patients with intravenous drug use (Wyler et al , 1975; Alvarez et al , 1990; Al Hazzaa et al , 1992; Equi and Green, 2001; Williams et al , 2006; Latorre, 2008; Jackson et al , 2014; Shah et al 2014). Moreover, a report described endophthalmitis due to S. marcescens in a woman with concurrent hospital-acquired S. marcescens pneumonia (Williams et al , 2006).…”

Outbreak of a Cluster with Epidemic Behavior Due to Serratia marcescens after Colistin Administration in a Hospital Setting

“…This organism is able to colonize the human gastrointestinal tract and skin for extended periods, being transmitted predominantly by person-to-person contact. Pneumonia, bloodstream infections, meningitis, and ocular and urinary tract infections can result from an S. marcescens infection (2)(3)(4)(5)(6). S. marcescens is also well known as a nosocomial pathogen and has been responsible for outbreaks, particularly in critically ill neonates and patients in intensive care units (2,(7)(8)(9).…”