Serratula tinctoria, a source of natural dye: Flavonoid pattern and histolocalization

Guinot, Pauline; Gargadennec, Annick; Fisca, Philippe La; Fruchier, Alain; Andary, Claude; Mondolot, Laurence

doi:10.1016/j.indcrop.2008.06.007

Cited by 27 publications

(15 citation statements)

References 28 publications

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“…All data obtained confirmed the identification of the two pure compounds present in the four selected fractions, which exhibited an effective antileishmanial activity (Table 1 and Figure 1). In addition, the structural identification of quercetin 3-O-methyl ether and strychnobiflavone were compared with literature records in order to prove to be identical compounds [20, 22]. …”

Section: Resultsmentioning

confidence: 99%

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Strychnos pseudoquinaand Its Purified Compounds Present an EffectiveIn VitroAntileishmanial Activity

Lage

Andrade

Lopes

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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The development of new and cost-effective alternative therapeutic strategies to treat leishmaniasis has become a high priority. In the present study, the antileishmanial activity of Strychnos pseudoquina St. Hil. was investigated and pure compounds that presented this biological effect were isolated. An ethyl acetate extract was prepared, and it proved to be effective against Leishmania amazonensis. A bioactivity-guided fractionation was performed, and two flavonoids were identified, quercetin 3-O-methyl ether and strychnobiflavone, which presented an effective antileishmanial activity against L. amazonensis, and studies were extended to establish their minimum inhibitory concentrations (IC50), their leishmanicidal effects on the intra-macrophage Leishmania stage, as well as their cytotoxic effects on murine macrophages (CC50), and in O+ human red blood cells. The data presented in this study showed the potential of an ethyl acetate extract of S. pseudoquina, as well as two flavonoids purified from it, which can be used as a therapeutic alternative on its own, or in association with other drugs, to treat disease evoked by L. amazonensis.

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Section: Resultsmentioning

confidence: 99%

“… a CD 3 OD; b DMSO- d 6 ; c DMSO- d 6 (Guinot et al 2009 [22]); d acetone- d 6 (Nicoletti et al 1984 [20]); e,f interchangeable.…”

Section: Figurementioning

confidence: 99%

Strychnos pseudoquinaand Its Purified Compounds Present an EffectiveIn VitroAntileishmanial Activity

Lage

Andrade

Lopes

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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“…The main dyeing components are flavonoids and specifically luteolin and luteolin‐7‐O‐glucoside (Andary, Prunac & Cardon ; Guinot et al . ) in the leaves and stems. In addition to these, Guinot et al .…”

Section: Structure and Physiologymentioning

confidence: 99%

“…In addition to these, Guinot et al . () used thin‐layer chromatography to indicate that kaempferol, luteolin‐3′‐7‐O‐diglucoside, luteolin‐3′‐O‐glucoside and luteolin‐4′‐O‐glucoside may possibly be present. Lech, Witkoś & Jarosz () analysed the constituents of the colorants in S. tinctoria and isolated chlorogenic acid and its isomers, luteolin‐O‐glucuronides, eriodictyol‐O‐glucuronide and diosmetin‐O‐glucuronides.…”

Section: Structure and Physiologymentioning

confidence: 99%

“…Serratula tinctoria was used as a source of yellow dye until the 19th Century, hence its alternative English name of Dyer's savoury and the specific epithet tinctoria derived from a Latin word meaning 'used for dyeing or staining'. The main dyeing components are flavonoids and specifically luteolin and luteolin-7-O-glucoside (Andary, Prunac & Cardon 1996;Guinot et al 2009) in the leaves and stems. In addition to these, Guinot et al (2009) used thin-layer chromatography to indicate that kaempferol, luteolin-3 0 -7-O-diglucoside, luteolin-3 0 -O-glucoside and luteolin-4 0 -O-glucoside may possibly be present.…”

Section: ( F ) B I O C H E M I C a L D A T Amentioning

confidence: 99%

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Biological Flora of the British Isles: Serratula tinctoria

Jefferson

Walker

2017

Journal of Ecology

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Summary This account presents information on all aspects of the biology of Serratula tinctoria L. that are relevant to understanding its ecological characteristics and behaviour. The main topics are presented within the standard framework of the Biological Flora of the British Isles: distribution, habitat, communities, responses to biotic factors, responses to environment, structure and physiology, phenology, floral and seed characters, herbivores and disease, history and conservation. Serratula tinctoria is a gynodioecious perennial forb of open or semi‐shaded habitats including grassland, heath, mire, open woodland and scrub and their ecotones. It is found throughout most of England and Wales but it is very rare in Scotland and absent from Ireland. Serratula tinctoria is found in Europe as far north as southern Sweden and Norway. It is absent from much of the Boreal biogeographical zone, including most of Fennoscandia and northern Poland, Russia and the Baltic States, and from the lowland Mediterranean zone. Serratula tinctoria occurs on soils overlying a wide variety of superficial deposits and sedimentary, metamorphic and igneous rocks, including ultramafic rocks. The pH range of these soils is wide, ranging from acidic to moderately alkaline but with nutrient status classed as oligotrophic, or more rarely mesotrophic. In mire or fen habitats, it occurs in topogenous or soligenous situations with a similar soil water pH range. It is able to tolerate a wide spectrum of soil water‐table conditions, ranging from very dry to flooded. Serratula tinctoria is pollinated by various insects of the orders Hymenoptera, Diptera and Lepidoptera, particularly bumblebees, hoverflies and butterflies. It produces phytoecdysteroids, which mimic a hormone that regulates insect development. The seed has a feathery pappus for wind dispersal and establishment is primarily from seed. However, it has strong dispersal limitation with slow migration rates into restored grasslands of 1 m year−1. The species has a short‐term persistent seed bank. Seedling recruitment is enhanced by disturbance that creates bare ground, increasing light flux and lower cover of bryophytes and litter, and reduced by higher nutrient availability and lack of management. Formerly the source of a yellow dye, S. tinctoria has declined in Britain since at least the late 19th Century primarily due to a combination of drainage, ploughing and agricultural improvement and, conversely, lack of management by cutting and grazing in its grassland, heath and mire habitats. There is evidence that the decline slowed or stabilised between the late‐1980s and the mid‐2000s, in part due to the positive impact of conservation via statutory protection on designated sites and wider measures delivered through agri‐environment schemes.

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Flavonoids in Subtribe Centaureinae (Cass.)Dumort.(Tribe Cardueae, Asteraceae): Distribution and¹³C‐NMR Spectral Data

Formisano

Rigano

Senatore

et al. 2012

Chemistry & Biodiversity

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Serratula tinctoria, a source of natural dye: Flavonoid pattern and histolocalization

Cited by 27 publications

References 28 publications

Strychnos pseudoquinaand Its Purified Compounds Present an EffectiveIn VitroAntileishmanial Activity

Strychnos pseudoquinaand Its Purified Compounds Present an EffectiveIn VitroAntileishmanial Activity

Biological Flora of the British Isles: Serratula tinctoria

Flavonoids in Subtribe Centaureinae (Cass.)Dumort.(Tribe Cardueae, Asteraceae): Distribution and¹³C‐NMR Spectral Data

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Serratula tinctoria, a source of natural dye: Flavonoid pattern and histolocalization

Cited by 27 publications

References 28 publications

Strychnos pseudoquinaand Its Purified Compounds Present an EffectiveIn VitroAntileishmanial Activity

Strychnos pseudoquinaand Its Purified Compounds Present an EffectiveIn VitroAntileishmanial Activity

Biological Flora of the British Isles: Serratula tinctoria

Flavonoids in Subtribe Centaureinae (Cass.)Dumort.(Tribe Cardueae, Asteraceae): Distribution and13C‐NMR Spectral Data

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Flavonoids in Subtribe Centaureinae (Cass.)Dumort.(Tribe Cardueae, Asteraceae): Distribution and¹³C‐NMR Spectral Data