SERS as a tool for determination of structurally related compounds: The case of sulfanilamide class antibiotics

Markina, Natalia E.; Goryacheva, Irina Yu.; Markin, Alexey V.

doi:10.1016/j.talanta.2024.126433

Talanta

2024

DOI: 10.1016/j.talanta.2024.126433

|View full text |Cite

SERS as a tool for determination of structurally related compounds: The case of sulfanilamide class antibiotics

Natalia E. Markina,

Irina Yu. Goryacheva,

Alexey V. Markin

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Determination of multiple analytes in urine using label-free SERS coupled with simple sample pretreatments

Markina,

Markin

2024

Analytica Chimica Acta

View full text Add to dashboard Cite

Determination of multiple analytes in urine using label-free SERS coupled with simple sample pretreatments

Markina,

Markin

2024

Analytica Chimica Acta

View full text Add to dashboard Cite

Study on the Rapid Limit Test for Six Sulfonamide Residues in Food Based on the TLC-SERS Method

Ma,

Zhang,

et al. 2024

Molecules

View full text Add to dashboard Cite

Sulfonamides are not only widely applied in clinics but also highly valued in animal husbandry. Recently, it has become common for sulfonamide residues to exceed the standard limits in food, which can affect human health. Current regulations limit these residues. Therefore, we constructed a new limit test method to rapidly determine the levels of sulfonamide residues. Six sulfonamides were detected using the latest method called TLC-SERS, namely, sulfamethasone (A), sulfamethazine (B), sulfadoxine (C), sulfamethoxydiazine (D), sulfamethoxazole (E), and sulfathiazole (F). The optimal conditions for SERS detection were investigated for these six drugs, and the separation effects of different TLC spreaders on them were compared. Then, we successfully established a separation system using dichloromethane–methanol–ammonia in a ratio of 5:1:0.25 (v/v/v), which provided good separation effects on the six drugs. The residues were preliminarily separated via TLC. A silver sol solution was added to the spot on the silica gel G plate at the corresponding specific shift values, and SERS detection was performed. The sample solution was placed on the spot under a 532 nm laser, and the SERS spectrum was collected and analyzed for the six sulfonamides. The results showed obvious variations in the SERS spectrum among the six sulfonamides, with the LODs being 12.5, 6.4, 6.3, 7.1, 18.8, and 6.2 ng/mL from A to F, respectively, and an RSD of <3.0%. Within 48 h, the SERS signal for each sulfonamide drug was kept stable, with an RSD of <3.0%. The detection results of 20 samples using the TLC-SERS method were consistent with those obtained by UPLC-MS/MS. The established TLC-SERS method is simple and fast, providing a useful reference for the rapid detection of residue limits in food.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

SERS as a tool for determination of structurally related compounds: The case of sulfanilamide class antibiotics

Cited by 2 publications

References 35 publications

Determination of multiple analytes in urine using label-free SERS coupled with simple sample pretreatments

Determination of multiple analytes in urine using label-free SERS coupled with simple sample pretreatments

Study on the Rapid Limit Test for Six Sulfonamide Residues in Food Based on the TLC-SERS Method

Contact Info

Product

Resources

About