Serum 25 hydroxyvitamin D in employees of a Middle Eastern university hospital

Gannagé‐Yared, Marie‐Hélène; Helou, Elie El; Zaraket, Vera; Akl, S. Abi; Antonios, L.; Moussalli, M.-L.; Wakim, Saria

doi:10.1007/s40618-014-0061-1

Cited by 14 publications

(16 citation statements)

References 32 publications

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“…Furthermore, our results indicated that patients with schizophrenia, as well as the healthy ones, had a vitamin D deficiency, similar to previous studies [2,4,36,37,40,41]. Other studies conducted in Lebanon had shown a hypovitaminosis D in the healthy population [35,[42][43][44][45].…”

Section: Discussionsupporting

confidence: 91%

Vitamin D Levels in Lebanese Patients with Schizophrenia: A Case-Control Study

Azar¹

2017

Ann Nutr Disord & Ther

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Objectives: To compare the vitamin D status in schizophrenics to that of healthy controls; secondary objectives were to assess the correlation between severe vitamin D deficiency and the severity of schizophrenia symptoms and to evaluate the potential factors influencing this status. Methods:A case-control study, conducted between March and July 2016, recruited 100 patients with schizophrenia and 100 controls with no known psychiatric disorders and matched for age and sex.Results: Schizophrenic patients had a more severe vitamin D deficiency compared to healthy controls (9% vs. 3%). Vitamin D insufficiency was found in 28% of schizophrenic patients compared to 37% in healthy controls (p=0.053). BCRS and MRSS scales were significantly associated with a more severe vitamin D deficiency (p=0.006). We couldn't detect any association between the total PANSS score and its three subscales with vitamin D deficiency (p>0.05). Lebanon has a high prevalence of 25(OH)-D deficiency in adults and older adults [23,24] however, data regarding vitamin D levels in psychiatric patients is still lacking. Therefore, the primary objective of this study was to compare the vitamin D status in schizophrenics to that of healthy controls; secondary objectives were to assess the

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Section: Discussionsupporting

confidence: 91%

Vitamin D Levels in Lebanese Patients with Schizophrenia: A Case-Control Study

Azar¹

2017

Ann Nutr Disord & Ther

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“…Our sample mean serum 25(OH)D level (28.15±13.93 ng/ml) was higher and prevalence rate of vitamin D deficiency (≤ 20 ng/ml) (32%) were lower than those reported in two studies involving samples of healthy Lebanese adults (Gannagé-Yared et al, 2014;Malaeb, Hallit, & Salameh, 2017); this could be attributed to differences in characteristics among study samples. Mean serum 25(OH)D level was found to be 15.61 ± 7.91 ng/ml and prevalence rate of vitamin D deficiency (< 20 ng/ml) was reported at 71.4% among a sample of 392 healthy private hospital employees (nurses, medical assistants, technicians, secretaries, medical engineers, administrative employees, etc., excluding doctors and medical students) aged 20-63 years (mean age= 41.02 ±11.3 years) (81% women); none of them had been taking vitamin D supplement.…”

Section: Discussioncontrasting

confidence: 87%

“…Mean serum 25(OH)D level was found to be 15.61 ± 7.91 ng/ml and prevalence rate of vitamin D deficiency (< 20 ng/ml) was reported at 71.4% among a sample of 392 healthy private hospital employees (nurses, medical assistants, technicians, secretaries, medical engineers, administrative employees, etc., excluding doctors and medical students) aged 20-63 years (mean age= 41.02 ±11.3 years) (81% women); none of them had been taking vitamin D supplement. Similar to our findings, there was no significant associations between serum 25(OH)D levels and age, sex, BMI, and sunscreen use; however, contrary to our study, serum 25(OH)D levels showed significant associations with educational level, and weekly hours of sun exposure (Gannagé-Yared et al, 2014). The two other studies looked at serum 25(OH)D levels and their determinants in samples of university students.…”

Section: Discussionsupporting

confidence: 70%

Vitamin D Levels and Depressive Symptoms’ Severity Among University Employees in Lebanon

Jaalouk

Boumosleh

Fatayri

2018

GJHS

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Background: Despite the evidence that the association between serum vitamin D level and susceptibility to depression is altered by ethnicity and vitamin D receptor gene polymorphisms, high prevalence of vitamin D deficiency, and parallel substantial burden of depression among Middle Eastern/ Arab adult populations, research exploring whether low serum vitamin D level is associated with increased risk of depression among Arab adult populations is almost non-existent.Objective: This study aims to investigate the relationship between serum vitamin D levels and severity of depressive symptoms among a sample of healthy Lebanese adults, controlling for multiple confounders.Methods: A total of 351 employees at a private university in Lebanon were surveyed. Information about sociodemographic, lifestyle habits, medical/ family history; and depressive symptoms were collected using a background questionnaire, international physical activity questionnaire -short form, and Patient Health Questionnaire, respectively. Anthropometric measurements and fasting blood samples were collected using standard methods. Serum 25-hydroxyvitamin D [25(OH)D] levels were measured by means of ELISA. Multiple linear regression analyses were conducted. A p-value of less than 0.05 was considered statistically significant.Results: Sample mean age was 42.36 years. In the fully adjusted model, higher depression scores were found to be border-line significantly (p= 0.058) associated with lower serum 25-(OH)D levels and significantly associated with younger age, female sex, lower income, chronic illness diagnosis, family history of mental illness, number of stressful life events, and intake of antidepressants. Conclusion:We did not find any significant independent association between serum 25(OH)D levels and severity of depressive symptoms in a sample of Lebanese employees of a private university.

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“…In Lebanon, Gannage-Yared et al studied 318 female hospital workers with a mean age of 40.4 ± 11 years and reported vitamin D deficiency (serum 25(OH)D < 23.5 nmol/L) in 25% and insufficiency (serum 25(OH)D 23.75–53.75 nmol/L) in 50% of women, with no significant correlations with BMI or age [34]. …”

Section: Prevalence Of Micronutrient Deficiencies In the Middle Eastmentioning

confidence: 99%

“…Data on micronutrient deficiencies in men residing in the Middle East appears limited and mainly focuses on vitamin D, with the highest deficiency and insufficiency levels reported in Lebanon at 27% and 54%, respectively [34], as well as in the UAE and KSA at ~40% [11,28,38]. …”

Section: Prevalence Of Micronutrient Deficiencies In the Middle Eastmentioning

confidence: 99%

The Prevalence of Micronutrient Deficiencies and Inadequacies in the Middle East and Approaches to Interventions

et al. 2017

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Micronutrient deficiencies and inadequacies constitute a global health issue, particularly among countries in the Middle East. The objective of this review is to identify micronutrient deficits in the Middle East and to consider current and new approaches to address this problem. Based on the availability of more recent data, this review is primarily focused on countries that are in advanced nutrition transition. Prominent deficits in folate, iron, and vitamin D are noted among children/adolescents, women of childbearing age, pregnant women, and the elderly. Reports indicate that food fortification in the region is sporadic and ineffective, and the use of dietary supplements is low. Nutrition monitoring in the region is limited, and gaps in relevant information present challenges for implementing new policies and approaches to address the problem. Government-sponsored initiatives are necessary to assess current dietary intakes/patterns, support nutrition education, and to reduce food insecurity, especially among vulnerable population groups. Public–private partnerships should be considered in targeting micronutrient fortification programs and supplementation recommendations as approaches to help alleviate the burden of micronutrient deficiencies and inadequacies in the Middle East.

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Serum 25 hydroxyvitamin D in employees of a Middle Eastern university hospital

Abstract: Vitamin D deficiency is common among hospital workers. This finding reinforces the need for vitamin D supplementation in these high-risk populations.

Cited by 14 publications

References 32 publications

Vitamin D Levels in Lebanese Patients with Schizophrenia: A Case-Control Study

Vitamin D Levels in Lebanese Patients with Schizophrenia: A Case-Control Study

Vitamin D Levels and Depressive Symptoms’ Severity Among University Employees in Lebanon

The Prevalence of Micronutrient Deficiencies and Inadequacies in the Middle East and Approaches to Interventions

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