Serum 25‐hydroxyvitamin D levels in hospitalized adults with community‐acquired pneumonia

Abstract

Hospitalized adults with CAP have lower 25OHD levels and would be associated with the severity of CAP.

Vitamin D and Influenza—Prevention or Therapy?

“…Intriguing effects were presented by Mamani et al [59] and Brance et al [60] in their studies. Both studies showed an inverse correlation between the level of 25(OH)D and the severity of CAP (community-acquired pneumonia), which was defined as the CURB65 score (confusion, uremia, respiratory rate, low blood pressure, ≥65 years).…”

“…Both studies showed an inverse correlation between the level of 25(OH)D and the severity of CAP (community-acquired pneumonia), which was defined as the CURB65 score (confusion, uremia, respiratory rate, low blood pressure, ≥65 years). In addition, according to Brance et al [60], higher 25(OH)D concentrations were found to be correlated with lower CCI (Charlson comorbidity index). Nanri et al [61], in a nested case-control study in a cohort of workers in four companies in Japan during the winter season, found lower influenza risk to be associated with vitamin D sufficiency (≥30 ng/mL), but only among unvaccinated participants.…”

Correlation Between Serum Levels of 25-Hydroxyvitamin D and Severity of Community-Acquired Pneumonia in Hospitalized Patients Assessed by Pneumonia Severity Index: An Observational Descriptive Study

“…As mentioned above, the correlation between the levels of vitamin D and pneumonia severity assessed by the CURB-65 index has also been evaluated [16][17]. CURB-65, also known as the CURB criteria, is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia [27].…”

“…Vitamin D also exerts immunomodulatory effects on these responses to the most common cause of bacterial pneumonia, Streptococcus pneumonia [14], which has been associated with long-term mortality in patients with CAP [15]. The correlation between levels of vitamin D and pneumonia severity assessed by the CURB-65 index, another clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia, has also been evaluated [16][17].…”

Vitamin D and acute respiratory infections: prevention or treatment?

“…Интересные данные были представлены Mamani et al [46] и Brance et al [47]. В своих исследованиях они показали обратную корреляцию между уровнем 25-гидроксикальциферола и тяжестью внебольничной пневмонии, оцениваемой по индексу CURB65 (спутанность сознания, уремия, частота дыхания, низкое артериальное давление, возраст ≥65 лет).…”