Serum Albumin as a Biomarker of Pulmonary Sarcoidosis Chronicity

Isma, S. Jabeen; Omar, Hesham R.; Sweiss, Nadera J.; Mirsaeidi, Mehdi

doi:10.5152/turkthoracj.2018.094

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…A 2019 study hinted at the potential role of serum albumin levels as a predictive marker for the duration of the disease. Nevertheless, being a retrospective study, it lacked the capacity to establish correlations between albumin levels and other acute-phase proteins, liver, and kidney functions [98].…”

Section: Serum Biomarkersmentioning

confidence: 99%

Phenotypes and Serum Biomarkers in Sarcoidosis

Della Zoppa,

Bertuccio,

Campo

et al. 2024

Diagnostics

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Sarcoidosis is a multisystem disease, which is diagnosed on a compatible clinical presentation, non-necrotizing granulomatous inflammation in one or more tissue samples, and exclusion of alternative causes of granulomatous disease. Considering its heterogeneity, numerous aspects of the disease remain to be elucidated. In this context, the identification and integration of biomarkers may hold significance in clinical practice, aiding in appropriate selection of patients for targeted clinical trials. This work aims to discuss and analyze how validated biomarkers are currently integrated in disease category definitions. Future studies are mandatory to unravel the diverse contributions of genetics, socioeconomic status, environmental exposures, and other sociodemographic variables to disease severity and phenotypic presentation. Furthermore, the implementation of transcriptomics, multidisciplinary approaches, and consideration of patients’ perspectives, reporting innovative insights, could be pivotal for a better understanding of disease pathogenesis and the optimization of clinical assistance.

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Section: Serum Biomarkersmentioning

confidence: 99%