2019
DOI: 10.5455/annalsmedres.2019.11.751
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Serum amyloid-a may be an early marker in diagnosis of preterm premature rupture of membrane and chorioamnionitis

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Cited by 3 publications
(8 citation statements)
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“…We also found that SAA1 levels were markedly increased in maternal circulation in preterm birth with chorioamnionitis when compared with gestational age-matched iatrogenic preterm birth (40). In addition to the rise of SAA levels in maternal circulation, SAA levels in cord blood were also significantly higher in patients with PPROM (115 µg/mL) than in patients without PPROM (26 µg/mL) (77). These results suggest that both mother and fetus may respond to PPROM, and the response may be particularly strong when chorioamnionitis is present.…”
Section: Pprom and Chorioamnionitissupporting
confidence: 54%
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“…We also found that SAA1 levels were markedly increased in maternal circulation in preterm birth with chorioamnionitis when compared with gestational age-matched iatrogenic preterm birth (40). In addition to the rise of SAA levels in maternal circulation, SAA levels in cord blood were also significantly higher in patients with PPROM (115 µg/mL) than in patients without PPROM (26 µg/mL) (77). These results suggest that both mother and fetus may respond to PPROM, and the response may be particularly strong when chorioamnionitis is present.…”
Section: Pprom and Chorioamnionitissupporting
confidence: 54%
“…Yang et al found that SAA 1 and 2 were among the proteins which were significantly elevated in maternal blood in lipopolysaccharide (LPS)-induced preterm birth in the mouse (75). In human studies, Koseoglu et al found that SAA levels in maternal blood were significantly elevated in the PPROM group compared to the control group (76), and Kayabas et al demonstrated that SAA levels in maternal circulation were further increased in patients with clinical chorioamnionitis (107 µg/mL) when compared with patients with only PPROM but not chorioamnionitis (21 µg/mL) (77). We also found that SAA1 levels were markedly increased in maternal circulation in preterm birth with chorioamnionitis when compared with gestational age-matched iatrogenic preterm birth (40).…”
Section: Pprom and Chorioamnionitismentioning
confidence: 99%
“…In four studies, there were no significant differences between the study and control groups in demographic and clinical characteristics such as maternal age (years), BMI, gravidity, parity, and gestational age at admission. One study shows a statistically significant difference in maternal age [ 22 ]. All included studies showed a statistically significant difference in serum SAA levels between the two groups.…”
Section: Resultsmentioning
confidence: 99%
“… The effect size and heterogeneity based on omitting different included studies [ 22 , 23 , 24 , 25 , 26 ]. …”
Section: Figurementioning
confidence: 99%
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