Serum and saliva magnesium in postmenopausal women with xerostomia

Agha‐Hosseini, Farzaneh; Mirzaii‐Dizgah, Iraj

doi:10.3109/13697137.2011.624212

Cited by 3 publications

(2 citation statements)

References 20 publications

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“…Due to the nature of diabetes, vitamin D 3 levels in serum or saliva, May be varying from one person to another and in various social, ethnic groups, in different geographical conditions and under different mechanisms requires extensive research for the understanding of the causes and possible mechanisms. In Agha Hosseini's study (2011) Salivary and serum levels of vitamin D 3 in postmenopausal women may be maintained in the normal range and have nothing to do with the feeling of dry mouth (Agha-Hosseini, Mirzaii-Dizgah, & Mirjalili, 2011). In healthy adults, about 85% of circulating vitamin D 3 , bind to vitamin D binding protein and there are less than 0.1% free in the plasma and plasma proteins to cross salivary membranes, are much larger and only low molecular weight compounds, be able to pass and it can be inferred that identification of higher amounts of vitamin D3 in saliva, can result from the presence of more vitamin D 3 -binding protein in saliva (Higashi et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Evaluation the Relationship Between Serum and Salivary Levels of 25(OH)Vit.D with Type II Diabetes in Newly Diagnosed Diabetics

Abdolsamadi¹,

Vahedi²,

Borzouei³

et al. 2018

JMBR

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Introduction: The International Diabetes Federation (IDF) Announces 415 million people around the world are suffering from diabetes. There is a high proportion of UDM (undiagnosed diabetes) at the level of the world and particularly in developing countries. The number of people with UDM in Iran in 2015 are 2197.96 per 1000. Vitamin D3 deficiency is associated with increased risk of type 2 diabetes and for a long time, been recognized as a risk factor for glucose intolerance. Salivary composition, as the mirror of oral health, its use as a diagnostic tool is increasing and diabetes is also can be effective on the flow rate of saliva and its compounds. Analysis of saliva can be used as part of the evaluation of endocrine function. Material and Methods: In this case-control study in 2016 in Hamadan, we selected 57 newly diagnosed patients with type 2 diabetes mellitus with mean aged 47.73 years and 57 healthy controls with mean aged 45.36 years. By using Spitting method, 5ml of completely unstimulated saliva samples were collected from diabetic patients and control subjects. The serum and saliva 25(OH)Vit.Dconcentrations were measured by ELISA. The results are analyzed by SPSS 16.Results: Significant difference was found in serum concentrations between the two groups (p<0.001). But in unstimulated whole salivary 1, 25(OH) 2D3 concentrations between the two groups, difference was not significant and the relationship, was reversed. There was a significant correlation (P=0.013) between serum and saliva 1, 25(OH) 2D3concentrations in the control group. In other words, the correlation was approximately 0.33. Correlation between serum and saliva 1, 25(OH) 2D3 concentrations in case group was not significant. Serum levels of 1, 25(OH) 2D3 in 21.1% of control group, showed the inadequate level (Vit.D3= 20-29ng/ml) and in the case group, showed the critical situation and overall 91.2% of the newly diagnosed diabetics, suffered from lack of vitamin D3. According to the salivary levels of 1, 25(OH) 2D3, in general, a total of 58% of the case group, have deficiency of vitamin D3.Conclusion: The results was confirmed vitamin D3 deficiency in participating in the study population (both case and control). The findings showed that there is lower concentration of 1, 25(OH) 2D3 in serum and after that in saliva in diabetic patients that newly diagnosed. Saliva would play a helpful diagnostic role in the early detection, the monitoring and progression of diabetes, but still serum is the better method for detecting vit.D3 levels and more research needs to be done on saliva for detecting Vit.D3 concentrations.

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Section: Discussionmentioning

confidence: 99%

Evaluation the Relationship Between Serum and Salivary Levels of 25(OH)Vit.D with Type II Diabetes in Newly Diagnosed Diabetics

Abdolsamadi¹,

Vahedi²,

Borzouei³

et al. 2018

JMBR

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“…Saliva, as compared to plasma, can be used to diagnose and evaluate disease progression. It is a biological fluid that can be collected easily, noninvasively, stress-free and several times without causing discomfort to patients compared to blood sampling (6,7). However, it is not usually used to diagnose diseases, like other biological samples.…”

Section: Introductionmentioning

confidence: 99%

Bilirubin in Saliva: A Potential Biomarker for Detecting Neonatal Jaundice

Dizgah¹,

Dizgah²,

Mirzaii‐Dizgah³

et al. 2019

Avicenna J Dent Res

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Background: Precise and quick diagnosis of jaundice in the neonates is of major medical and economic importance. Biomarkers in serum are regularly applied in clinical settings. Nevertheless, saliva could be a substitute to assess biomarkers. In this study, we aimed to detect the probable association between salivary and serum levels of bilirubin in jaundiced neonates. Methods: A case-control survey was performed on 30 healthy neonates and 30 neonates with jaundice hospitalized in Mirzakhochekkhan and Baharloo hospitals, Tehran, Iran. Bilirubin levels were assayed in serum and unstimulated whole saliva by a photometric method. Pearson correlation and Student's t tests were used for statistical analysis. Results: The mean salivary and serum levels of total bilirubin were significantly higher in the neonates with jaundice compared to healthy individuals. A moderate correlation was observed between serum and salivary concentrations of total bilirubin. Conclusions: Serum and salivary levels of bilirubin are meaningfully correlated in jaundiced neonates. This correlation may facilitate the monitoring and evaluation of bilirubin levels non-invasively for jaundice.

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World Workshop on Oral Medicine VIII: Development of a core outcome set for dry mouth: a systematic review of outcome domains for salivary hypofunction

Simms

Kuten-Shorrer

Wiriyakijja

et al. 2023

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Serum and saliva magnesium in postmenopausal women with xerostomia

Abstract: Serum magnesium level appears to be associated with xerostomia in menopause.

Cited by 3 publications

References 20 publications

Evaluation the Relationship Between Serum and Salivary Levels of 25(OH)Vit.D with Type II Diabetes in Newly Diagnosed Diabetics

Evaluation the Relationship Between Serum and Salivary Levels of 25(OH)Vit.D with Type II Diabetes in Newly Diagnosed Diabetics

Bilirubin in Saliva: A Potential Biomarker for Detecting Neonatal Jaundice

World Workshop on Oral Medicine VIII: Development of a core outcome set for dry mouth: a systematic review of outcome domains for salivary hypofunction

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