Serum and Salivary Immunoglobulins levels in Tobacco Smokers of Baghdad Governorate

Abstract

It was shown that tobacco smoking was a major environmental factor which altered numerous changes in both antibody and cell mediated immune responses leading to increase the capability of the individual to develop various inflammatory and autoimmune diseases, thus the current study aimed to assess the levels of both serum and salivary Igs in 35 individuals who smoking tobacco and compared them to 35 non-smokers group. Results of this study revealed a slightly but non-significant increased (p<0.05) in the serum and salivary levels of IgM in smokers as compared to non-smokers, while the serum and salivary levels of both IgG and IgA shown a significantly decreased (p≤0.05) in smokers as compared to non-smokers group. No positive correlation was found in the serum and salivary Igs levels in smokers. Body mass index (BMI) and smoking index (SI) were calculated for the smokers group, however, no significant differences were found in both serum and salivary Igs levels.