“…Thus, fish liver is a very interesting model for the study of interactions between environmental factors and hepatic functions. Under Cd stress, there were tremendous alterations of hepatocellular structure such as severe pyknotic nuclei, considerable lipid inclusions, the swelling and vesiculation of mitochondria with disappeared cristae, and absence of rough endoplasmic reticulum, similar to the reports about effects of metal exposure on alterations of histology and and ultrastructure in fish (Barillet et al, 2010;Lee et al, 2014;Liu et al, 2011;Song et al, 2016). Unlike Cd exposure, Zn weakly induced changes in hepatocellular structure.…”