Serum androgen levels in healthy premenopausal women with and without sexual dysfunction: Part B: Reduced serum androgen levels in healthy premenopausal women with complaints of sexual dysfunction

Guay, André T.; Jacobson, Jerilynn; Munárriz, Ricardo; Traish, Abdulmaged M.; Talakoub, Lily; Quirk, Frances; Goldstein, Irwin; Spark, Richard F.

doi:10.1038/sj.ijir.3901176

Cited by 59 publications

(57 citation statements)

References 29 publications

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“…In the same study, there was no correlation between serum androgen levels and FSD. However, some other studies, on both pre-and postmenopausal women and women, after surgically induced menopause, have demonstrated a correlation between reduced sexual desire and low androgen levels [99][100][101][102].…”

Section: Aging and Fsdmentioning

confidence: 99%

Female sexual dysfunction

2007

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Female sexual dysfunction is a common problem with detrimental effects on woman's quality of life. It also has an economical and societal impact. It is defined as disorders of sexual desire, arousal, orgasm, and sexual pain, which lead to personal distress. The etiology of sexual dysfunction is frequently multifactorial as it relates to general physical and mental well-being, quality of relationship, past sexual functioning, social class, education, employment, life stressors, personality factors, the presence of a sexual partner, and partner's age and health. It is very important to adopt the most efficient approach to gather information, and this may be achieved via standardized questionnaires or open-ended questions. Therapy should be tailored according to the patient's needs and may involve a multidisciplinary team approach including psychosexual counselor/sexologist/therapist and the physician. There is still more work needed to optimize the care of women with this problem. Priority should be given to international standardization and training of health care professionals.

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Section: Aging and Fsdmentioning

confidence: 99%

Female sexual dysfunction

2007

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“…Women seem able to be affected sexually through estrogenic activation (Guillermo, Manlove, Gray, Zava, & Marrs, 2010) and androgenic modulation (Guay et al, 2004). Accordingly, impaired sexual functioning in postmenopausal women responds to administration of estrogen (Yang, Mlček, & Kittnar, 2013) and/or androgens (Glaser & Dimitrakakis, 2013).…”

Section: Discussionmentioning

confidence: 98%

A Pilot Study on Tamoxifen Sexual Side Effects and Hand Preference in Male Breast Cancer

et al. 2015

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Recent clinical and imaging studies suggest that sex hormones modulate sexuality according to a psychophysiologic process of lateralization of the brain, with androgens playing a greater role in sexual functioning of left hemibrain/right handedness and estrogens possibly for right hemibrain/left handedness. Based on this perspective, the current study attempted to specify the relationship between hand preference, estrogens, and sexual function in subjects with male breast cancer, taking into account the sexual side effects of tamoxifen as the agent for inhibiting estrogen action. Twenty-eight Romanian men-17 right-handed and 11 left-handed-undergoing treatment with tamoxifen for male breast cancer participated in this study. These men were assessed both prior to and during tamoxifen treatment using the International Index of Erectile Function, a standardized instrument used for the evaluation of various aspects of sexual functioning, including erectile function (EF), orgasmic function (OF), sexual desire (SD), and overall functioning (OF). A main effect for handedness was found on EF, OF, SD, and OS scales, with right-handed men showing higher functioning than left-handed men. Regarding interaction effects, the left-handed group of men showed greater decreased sexual functioning during tamoxifen (on three subscales: OF, SD, OS) compared to right-handed men. Further research should be conducted in order to support and refine this potential lateralized process of sexual neuromodulation within the brain.

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“…Eine Patientin, welche bei niedrigen Androgenspiegeln klinische Symptome eines Androgenmangels zeigt, wird eher von der Therapie profitieren, als eine Frau, die trotz Androgenmangels symptomfrei ist. Eine eindeutig klassifizierbare Beziehung zwischen endogenen Androgenen und der weiblichen Sexualität ließ sich bisher jedoch nicht darstellen [7,12,19,39].…”

Section: Cmeunclassified

Weibliche sexuelle Dysfunktion

2008

Gynäkologe

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Die weibliche sexuelle Dysfunktion ("female sexual dysfunction", FSD) ist ein weit verbreitetes Leiden mit einer Prävalenz in Deutschland von etwa 38%. Störungen der weiblichen Sexualität betreffen bleibende oder wiederkehrende Beeinträchtigungen der Libido, der subjektiven und genitalen Erregung, der Orgasmusfähigkeit und koital verursachte Schmerzen. Es werden eine Über-sicht über die Epidemiologie, die aktuellen Definitionen der einzelnen Bereiche der FSD und die Pathophysiologie sowie Empfehlungen zur Therapie gegeben. SchlüsselwörterWeibliche sexuelle Dysfunktion · Libidostörung · Erregungsstörung · Orgasmusstörung · Koitale Schmerzen Female sexual dysfunction AbstractFemale sexual dysfunction (FSD) is a very common disorder in Germany with a prevalence of approximately 38%. FSD includes persistent or recurrent disorders of sexual desire, disorders of subjective or genital arousal and pain during intercourse. An overview of the epidemiology, the current definitions of the single domains of FSD, the pathophysiology and recommendations on the treatment of FSD is given.

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Serum androgen levels in healthy premenopausal women with and without sexual dysfunction: Part B: Reduced serum androgen levels in healthy premenopausal women with complaints of sexual dysfunction

Cited by 59 publications

References 29 publications

Female sexual dysfunction

Female sexual dysfunction

A Pilot Study on Tamoxifen Sexual Side Effects and Hand Preference in Male Breast Cancer

Weibliche sexuelle Dysfunktion

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