Serum Androgen Levels in Women who Have Recurrent Miscarriages and their Correlation with Markers of Endometrial Function

Comparison of embryological and clinical outcome in GnRH antagonist vs. GnRH agonist protocols for in vitro fertilization in PCOS non-obese patients. A prospective randomized study

“…Decreased LH concentrations result in estradiol production impairment, follicle selection derangement, inability of luteinization and ovulation after hCG administration [46]. Increased LH concentrations are believed to be responsible for poor oocytes quality, low fertilization rate and high miscarriage percentage in patients with PCOS [47,48]. Optimal concentration of LH needed to most favorable COH became the subject of many studies and discussions.…”

The Pathophysiology of Miscarriage in Women with Polycystic Ovary Syndrome. Review and Proposed Hypothesis of Mechanisms Involved

“…However, it has been more recently demonstrated that in women with elevated circulating LH concentrations and a history of recurrent miscarriage, suppression of endogenous LH release before conception did not improve live birth rates 38 . Other studies have also failed to corroborate elevated LH as a risk factor for miscarriage in PCOS 39,40 .…”

Occurrence of Chromosomal Alterations in Recurrent Spontaneous Abortion Couples: A Case-Only Study from Kashmir, North India

“…Subnormal hormone production or abnormal endometrial response to circulating steroid hormones is one another cause of miscarriages [9,13]. Besides, several other maternal endocrinological abnormalities such as uncontrolled diabetes, high androgen levels, hyperprolactinaemia, thyroid dysfunction, and obesity have been implicated as etiological factors for RSA [14,15,16,17,18,19] . Among all, the genetic factors causing RSA are, however, difficult to study because the fetus is lost at an early stage of development and is therefore difficult to examine.…”