Serum antibody levels against t mycoplasmas in two north american indian populations predisposed to spondylitis

Ford, Denys K.; Henderson, Elizabeth

doi:10.1002/art.1780190614

Cited by 10 publications

(2 citation statements)

References 12 publications

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“…Of particular interest is that PAbs do not exhibit such polyreactivity with reference strains but they show cross-reactivity between serotype 2 and 5 reference strains. This crossreactivity has been observed by many investigators (1,2,8,18,19,20,24,27).…”

supporting

confidence: 75%

Development of Monoclonal Antibodies against Ureaplasma urealyticum Serotypes and Their Use for Serotyping Clinical Isolates

Echahidi

Muyldermans

Lauwers

et al. 2000

Clin Diagn Lab Immunol

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Monoclonal antibodies (MAbs) against Ureaplasma urealyticum serotype 2, 5, 7, 8, 10, 11, 12, and 13 reference strains were developed. The reactivities of these MAbs with the 14 serotype reference strains was verified by colony immunofluorescence assay and Western blot assay. MAbs against serotypes 2, 7, 10, 11, and 12 were serotype specific, whereas MAbs against serotypes 5, 8, and 13 showed cross-reactivity. All MAbs against serotype 5 were cross-reactive with serotype 2, and one showed, in addition, cross-reactivity to serotypes 9 and 10. Mutual cross-reactivities were observed between MAbs against serotypes 8 and 13. The usefulness of the MAbs for the serotyping of U. urealyticum strains was evaluated by serotyping 21 selected clinical isolates. A complete set of MAbs (the newly developed MAbs and the previously described MAbs against serotypes 1, 3, 4, 6, 9, and 14) as well as a complete set of polyclonal antibodies (PAbs), PAbs 1 to 14, were used. MAbs were able to identify 18 of 21 isolates including 2 isolates with mixed serotypes. Polyreactivity, which occurred with 19 of the 21 isolates with PAbs, was not observed by the use of MAbs. MAbs seem to be a more valuable tool than PAbs for serotyping and could help in investigating a possible link between the expression or variability of the serotype-specific antigens and pathogenicity.

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supporting

confidence: 75%

Development of Monoclonal Antibodies against Ureaplasma urealyticum Serotypes and Their Use for Serotyping Clinical Isolates

Echahidi

Muyldermans

Lauwers

et al. 2000

Clin Diagn Lab Immunol

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“…Subsequently, we further extended Black's classification by the identification of a tenth serotype, strain Westem. Lin, Kass, and co-workers used a complement-dependent mycoplasmacidal assay (that gives titers similar to those obtained by the MIT [6]) to develop a separate, 11-member serotyping scheme for U. urealyticum (10). We report here our attempt to correlate the two independent schemes, using the modified MIT (16) and colony epifluorescence (CEF) tests (20).…”

mentioning

confidence: 99%

Expanded serotyping scheme for Ureaplasma urealyticum strains isolated from humans

Robertson¹,

Stemke²

1982

J Clin Microbiol

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For the last decade the serological heterogeneity of strains of Ureaplasma urealyticum isolated from humans has been represented by eight serotypes. We have identified two additional serotypes, strains Vancouver and Western. Using a modified metabolic inhibition test and a colony indirect epifluorescence method, we tested antisera to the above 10 types against the 11 members of the independent Lin-Kass classification. Four of the latter, K2, U24, U26, and U38, showed unique specificities; these were confirmed by reciprocal testing with antisera prepared against the respective strains. With the addition of these strains, the serotyping scheme now has 14 members. Since this expanded classification allows greater discrimination between strains, it will allow also for their future characterization. It provides, in addition, a potentially more effective epidemiological tool.

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Yersinia‐Related Arthritis in the Pacific Northwest

Ford

Henderson

Price

et al. 1977

Arthritis & Rheumatism

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Serologic evidence ofArthritis following Yersinia enterocolitica infection has been well described in Scandinavia (1-4) but not in North America. The arthritis can be associated with erythema nodosum ( 5 ) or with Reiter's syndrome (6), though frequently it occurs without either. Sacroiliitis and spondylitis are recognized sequelae, and the predisposition of HLA-B27 individuals to arthritis following yersinial infection is established (7). In 1975 a study

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Serum antibody levels against t mycoplasmas in two north american indian populations predisposed to spondylitis

Cited by 10 publications

References 12 publications

Development of Monoclonal Antibodies against Ureaplasma urealyticum Serotypes and Their Use for Serotyping Clinical Isolates

Development of Monoclonal Antibodies against Ureaplasma urealyticum Serotypes and Their Use for Serotyping Clinical Isolates

Expanded serotyping scheme for Ureaplasma urealyticum strains isolated from humans

Yersinia‐Related Arthritis in the Pacific Northwest

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