Serum Bile Acids Concentrations in Healthy and Clinically Ill Neonatal Foals

Barton, Michelle Henry; LeRoy, Bruce E.

doi:10.1892/0891-6640(2007)21[508:sbacih]2.0.co;2

Cited by 15 publications

(38 citation statements)

References 11 publications

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“…The high levels of unconjugated bilirubin indicated that hemoglobin are too much destroyed. Although in this experiment total bilirubin significantly increased in treatment BW (1.54 mg/dL), but this value was in the normal range of total bilirubin mature in horses (0.1-1.9 mg/dL) (Barton & LeRoy 2007).…”

Section: Serum Biochemical Parameterscontrasting

confidence: 70%

Fecal volatile fatty acids and blood metabolites in the Turkmen horse associated with type and source of cereal grains

Direkvandi

Kalantari

2018

Journal of Applied Animal Research

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In this experiment, corn -oat, barley -wheat and barley -oats were used as a source of starch in 1, 2 and 3 rations respectively. The ratio of concentrate to forage in all treatments were 35:65. The results showed the concentration of total protein and cholesterol were not affected by the type and source of cereal grains (P > 0.05). Serum glucose and triglyceride concentration significantly increased in corn -oats treatment (P < 0.05). Also, in this experiment total volatile fatty acids (VFA), acetate (A), propionate (P) and A/P concentrations were not affected by the type of cereal grains (P > 0.05), but valerate and butyrate concentrations significantly increased in barley -wheat treatment (P < 0.05). On the other hand, concentrations of isobutyrate and isovalerate significantly increased in corn -oats treatment (P < 0.05). Fecal pH, were not significantly different between corn -oats and barley -oats treatments (P > 0.05), although the lowest pH was observed in barley -wheat treatment (6.02). According to the results, treatment 1 (corn -oats) improved fecal VFA and blood metabolites in the comparison of the other treatments.ARTICLE HISTORY

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Section: Serum Biochemical Parameterscontrasting

confidence: 70%

Fecal volatile fatty acids and blood metabolites in the Turkmen horse associated with type and source of cereal grains

Direkvandi

Kalantari

2018

Journal of Applied Animal Research

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“…The working diagnosis for this filly was encephalopathy secondary to gastrointestinal hyperammonaemia. Ammonia is normally produced within the intestinal tract following bacterial degradation of endogenous and exogenous protein, which occurs predominately in the caecum and colon (Wootton and Argenzio 1975; Mair and Jones 1995), where ammonium diffuses into the portal circulation to the liver for removal via the urea cycle (Barton and LeRoy 2007). In some situations, ammonium can accumulate within the circulation, leading to signs of encephalopathy.…”

Section: Discussionmentioning

confidence: 99%

“…An abdominal ultrasonographic examination revealed no abnormalities. Further biochemical analysis revealed a hyperammonaemia of 159 µmol/l (rr <50 µmol/l in mature horses) and evidence of mild increases in SDH (13.0 u/l, rr 0.7–4.5 u/l) and serum bile acids (17.9 µmol/l, rr 10.6–15.8 µmol/l) (Barton and LeRoy 2007). The CBC revealed a neutrophilia: 23.60 × 10 9 (rr 5.4–12.3 × 10 9 ), consisting of a mature neutrophilia (94% neutrophils) and blood lactate increased to 2.8 mmol/l.…”

Section: Clinical Detailsmentioning

confidence: 99%

Gastrointestinal hyperammonaemia in a 35‐day‐old Warmblood‐cross filly

Unt

McSloy

Kerbyson

et al. 2011

Equine Veterinary Education

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“…Comparados com os neonatos equinos, os recém-nascidos asininos da raça Martina Franca possuem contagem de hemácias menor no primeiro dia de vida (7,,15 x10 6 /µL) e com sete dias (7,(1)(2)(3)(4)(5)(6)(7)8 STONEHAM, 2006;GRONDIN;DEWITT, 2010).…”

Section: Revisão De Literaturaunclassified

“…Para asininos, os valores de neutrófilos segmentados ao nascimento (3,(6)(7)6 x10 3 /µl), 1 (2,9-6,7 x10 3 /µl) e 7 dias (4,(6)(7)7 (4,(4)(5)9 g/dL) e asininos (3,(2)(3)(4)(5)(6)6 g/dL) possuem valores inferiores aos de adultos, porém após à ingestão do colostro ocorre um aumento das concentrações, tanto nos equinos (5,2-8,0 g/dL) como nos asininos (3,7 g/dL) . Porém os valores de albumina não sofrem alteração durante os primeiros meses de vida .…”

Section: Revisão De Literaturaunclassified

<b>Avaliação dos parâmetros etológicos, laboratoriais e do perfil oxidativo de neonatos muares no primeiro mês de vida:</b> um comparativo com equinos

Riccio¹

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The aim of the present study was to evaluate vitality, behavioral and laboratory parameters and oxidative profile of newborn mules, comparing with horses during the first month of life. The foals were monitored just after delivery and Apgar score was assessed at 0, 5, 10, 30 and 60 minutes postpartum. Foal's postpartum behavior were timed (time to get in sternal recumbency, to start suckle reflex, to stand, to ingest colostrum and to eliminate meconium) and the need of enema was evaluated.Time to eliminate placenta and weight were recorded and foal's weight. The relationship between placental and foal weight was calculated for the mule's group.Laboratory evaluation included hematological and biochemical parameters, while lipid peroxidation was measured using TBARS and protein oxidation. Glutathione peroxidase activity, superoxide dismutase and total, indirect and direct bilirubin were used to evaluate the antioxidant profile. Apgar score at birth, 5, 10 and 30 minutes after birth was higher in mules. Mules started nursing colostrum earlier than horses, however elimination of meconium started later. Mares pregnant with mules eliminated fetal membranes earlier. Foal's and placental weight were similar between groups.There was no correlation between placental and foal's weight. Mules had higher MCHC, platelets, albumin, calcium, chloride, iron and magnesium, while total leukocytes, segmented neutrophils, lymphocytes, neutrophil:lymphocyte ratio, fibrinogen, BT, BD, BI, cholesterol and CK were lower in mules compared to horses.Interaction was found between group and time for red blood cells, hematocrit, hemoglobin, total leukocytes, segmented neutrophils, glucose, urea, albumin, triglycerides, cholesterol, CK and iron. Oxidative profile results showed no interaction between group and time for the analyzed variables. TBARS was lower in mules, while GPx activity was higher. There was a progressive TBARS decrease over time in the studied neonates, with GPx remaining constant at birth and 7 days, with a significant increase at 30 days. Time and group did not affect protein oxidation. SOD did not have a group effect and its activity was constant between analyzed times, except at 1 hour, when activity was lower than 6 hours, 7 and 30 days. Bilirrubins were lower in mules. Based on the differences found between species, this study offers reference values for behaviour, hematology, biochemistry and oxidative aspects in healthy mule neonates during the first month of life, and it can be useful for diagnosis and treatment of compromised neonates.Keywords: Hematology. Biochemistry. Apgar. Oxidative balance. Behavior. LISTA DE TABELASTabela 1 -Média ± erro padrão do escore Apgar modificado durante a primeira hora 4-6 moderada asfixia; 0-3 severa asfixia.A literatura descreve a importância de avaliar a vitalidade associada ao comportamento neonatal equino após o parto, a fim de identificar um neonato anormal nos primeiros momentos da vida. O potro normal se posiciona em decúbito esternal em até 5 minutos, inicia reflexo de sucç...

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Serum Bile Acids Concentrations in Healthy and Clinically Ill Neonatal Foals

Abstract: SBA concentrations in foals are significantly higher in the early neonatal period, underscoring the importance of using age-matched references when evaluating clinical pathology values during the neonatal period.

Cited by 15 publications

References 11 publications

Fecal volatile fatty acids and blood metabolites in the Turkmen horse associated with type and source of cereal grains

Fecal volatile fatty acids and blood metabolites in the Turkmen horse associated with type and source of cereal grains

Gastrointestinal hyperammonaemia in a 35‐day‐old Warmblood‐cross filly

<b>Avaliação dos parâmetros etológicos, laboratoriais e do perfil oxidativo de neonatos muares no primeiro mês de vida:</b> um comparativo com equinos

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