2014
DOI: 10.1096/fasebj.28.1_supplement.136.7
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Serum C‐peptide is positively associated with the presence of colorectal adenomas (136.7)

Abstract: Activation of the insulin ‐‐ insulin‐like growth factor (IGF) signaling axis is hypothesized to increase colon cancer risk. The aim of this study was to determine if serum factors related to insulin or insulin signaling were associated with advanced colon polyps in males. 126 men (48 ‐ 65 yr) were recruited at time of colonoscopy, and blood was collected. Odds ratios were determined using logistic regression for polyp number and polytomous logistic regression for polyp severity. 29% of the men in our study had… Show more

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