2003
DOI: 10.1016/s1567-5769(02)00216-3
|View full text |Cite
|
Sign up to set email alerts
|

Serum concentrations of growth factors in women with and without endometriosis: the action of anti-endometriosis medicines

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

2
48
2
4

Year Published

2004
2004
2022
2022

Publication Types

Select...
6
3

Relationship

0
9

Authors

Journals

citations
Cited by 89 publications
(56 citation statements)
references
References 27 publications
2
48
2
4
Order By: Relevance
“…Analyzing the VEGF serum levels in this present study, we demonstrated that the VEGF serum levels were statistically significantly higher in endometriosis patients compared to the control (P50.0001) which is in agreement with the findings reported by Matalliotakis et al [2003] in the Caucasian population (P50.001) but in contrast with those conducted by Kianpour et al [2013]. Additionally, we reported a significant association of the +936 CT genotype with an increased VEGF serum levels than the CC and TT genotypes (P50.0001).…”
Section: Discussionsupporting
confidence: 93%
“…Analyzing the VEGF serum levels in this present study, we demonstrated that the VEGF serum levels were statistically significantly higher in endometriosis patients compared to the control (P50.0001) which is in agreement with the findings reported by Matalliotakis et al [2003] in the Caucasian population (P50.001) but in contrast with those conducted by Kianpour et al [2013]. Additionally, we reported a significant association of the +936 CT genotype with an increased VEGF serum levels than the CC and TT genotypes (P50.0001).…”
Section: Discussionsupporting
confidence: 93%
“…Some studies have actually reported no significant difference in VEGF serum levels in patients with endometriosis compared with controls [24,25]. In contrast, other authors have shown a significant increase in circulating levels of VEGF among women with endometriosis [20,21,22,23]. In our study, we found no significant modulation of VEGFA mRNA levels in the peripheral blood of patients with endometriosis compared to controls.…”
Section: Discussioncontrasting
confidence: 89%
“…Previous studies have indicated a significant increase in VEGF and its mRNA expression in endometriotic lesions compared to controls or eutopic endometrium [15,16,17,18,19]. Contradictory results have been reported concerning peripheral blood levels of VEGF in women with or without endometriosis; some published data reported higher levels in cases of endometriosis [20,21,22,23], while other data reported no differences at all [24,25]. …”
Section: Introductionmentioning
confidence: 99%
“…There is evidence that these drugs possess anti-angiogenic activity as well. While estrogen increases VEGF-A expression, 33 progesterone, dydrogesterone and dihydrodydrogesterone, 60 such as danazol, 61 reduce VEGF-A levels. Importantly, dienogest, an oral progestin, inhibited development and maturation of neovessels in a rat endometriosis model.…”
mentioning
confidence: 99%