2010
DOI: 10.3390/ijms11062281
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Serum Concentrations of TNF α and Its Soluble Receptors in Patients with Adrenal Tumors Treated by Surgery

Abstract: The peripheral blood levels of TNF α and its soluble receptors were studied in 39 patients with malignant and benign adrenal tumors treated by adrenalectomy. The concentrations of TNF α were significantly elevated in patients with malignant tumors of the adrenal cortex and in patients with Conn’s syndrome compared to control. In patients with non-functioning adenomas and pheochromocytomas, TNF α levels were similar to those detected in the control. In subjects with myelolipomas, the serum concentration of TNF … Show more

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Cited by 3 publications
(2 citation statements)
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“…TNF can be released by macrophages during debris cleaning in the gap as part of the inflammatory response during the first healing stage [2]. Moreover, TNF levels are one order of magnitude greater during inflammation compared with normal physiological levels [31,32].…”
Section: Inflammatory Signalling In the Periosteal Bordermentioning
confidence: 99%
“…TNF can be released by macrophages during debris cleaning in the gap as part of the inflammatory response during the first healing stage [2]. Moreover, TNF levels are one order of magnitude greater during inflammation compared with normal physiological levels [31,32].…”
Section: Inflammatory Signalling In the Periosteal Bordermentioning
confidence: 99%
“…Following adrenalectomy, TNFα levels decreased in patients with ACC, non-functioning ACA and in patients with aldosteronomas. On the other hand, reduction of TNF1-R and TNF2-R serum levels was observed only in patients with unilateral aldosteronomas (34).…”
Section: Extrinsic Apoptosis Signaling Pathway Alterationsmentioning
confidence: 95%