Serum Ferritin and Oxidative Stress in Patients Undergoing Hemodialysis

The association of markers of oxidative-inflammatory status with malnutrition in hemodialysis patients with serum ferritin lower than 500 ng/mL

“…33 Previous evidence has shown that in renal patients on hemodialysis treatment enhanced oxidative-inflammatory stress may be associated with iron load and this may contribute to iron functional deficiency by making it difficult to attain the target hematocrit. [4][5][6][34][35][36][37][38] However, the lowest level of ferritin to maintain control of anemia without inducing oxidative tissue damage and increasing the risk of infections and cardiovascular diseases is still unknown. 38 Senol et al 39 found that 34 well-nourished HD patients had higher hsCRP and lipid peroxidation products (red blood cell malondialdehyde) when compared with 22 healthy controls.…”