Serum immune responses in common carp (Cyprinus carpio L.) to paraquat exposure: The traditional parameters and circulating microRNAs

Ma, Jing; Li, Yuanyuan; Wu, Meng‐Hao; Zhang, Can; Che, Yuqing; Li, Weiguo; Li, Xiaoyü

doi:10.1016/j.fsi.2018.02.046

Cited by 58 publications

(11 citation statements)

References 82 publications

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“…The high levels of MDA, BUN, AST and ALT and the low levels of complement C3, C4, SOD and T‐AOC were found when the dietary content of EHPB was ≥255 g/kg. The low levels of SOD and T‐AOC indicated that the functions of scavenging oxygen free radicals and prevention of lipid peroxidation were declined in blood (Ma et al., 2018). Increased lipid peroxidation leads to formation of MDA and the content of MDA reveals the degree of the free radical attack.…”

Section: Discussionmentioning

confidence: 99%

Effects of enzymatic hydrolysates from poultry by‐products (EHPB) as an alternative source of fish meal on growth performance, hepatic proteome and gut microbiota of turbot ( Scophthalmus maximus )

et al. 2020

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Fish meal (FM) is the major protein source in diet of aquaculture animal, especially carnivorous species, like turbot (Scophthalmus maximus). Turbot is a native European seawater fish and has now been introduced to the worldwide. Aquaculture production of turbot becomes increasingly important due to its high commercial value (FAO, 2014). As a typical carnivorous fish, turbot requires high amounts of dietary crude protein (about 50% of dry dietary matter), which mainly relies on FM

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Section: Discussionmentioning

confidence: 99%

Effects of enzymatic hydrolysates from poultry by‐products (EHPB) as an alternative source of fish meal on growth performance, hepatic proteome and gut microbiota of turbot ( Scophthalmus maximus )

et al. 2020

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“…The nonspecific immune response plays a major role in the fish immune response (Qinghui and Sen ), with AKP, acid phosphatase (ACP) and lysozyme (LZM) (Ma et al . ; Yi et al . ).…”

Section: Introductionmentioning

confidence: 99%

Effects of different diets on the intestinal microbiota and immunity of common carp ( Cyprinus carpio )

Yang

Luo

et al. 2019

J Appl Microbiol

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Aims: An 8-week trial was performed to evaluate the differences in the intestinal microbiota and immune function of common carp (Cyprinus carpio)fed different diets. Methods and Results: The fish (initial weight 492Á6 AE 30 g, n = 270) were randomly divided into three groups with three replicates and were fed earthworms (group A), earthworms + duckweed (group M) or duckweed (group P) respectively. The diversity and dominant microbiota of the intestinal bacteria were detected by denaturing gradient gel electrophoresis, and the abundance of dominant bacteria was quantified by qPCR. Additionally, the activities of some nonspecific immune enzymes and antioxidant enzymes were determined. The results showed that higher diversity and abundance of intestinal microbiota were observed in group M and group P (P < 0Á05). Based on the intestinal microbiota, Cetobacterium was only detected in the intestines of common carp in group A, and Bacillus was identified in groups M and P. Additionally, a higher abundance of Bacteroidetes and Firmicutes was also found in the intestine in group P than in group A (P < 0Á05). Interestingly, the higher activities of immune enzymes were detected in intestine of common carp in group M, such as acid phosphatase, phosphatase (AKP), lysozyme, total antioxidant capacity, superoxide dismutase, catalase, glutathione peroxidase. In addition, the lower level of metabolites were also detected, such as nitric oxide and malondialdehyde. Conclusions: Our results indicate that the intestinal microbiota and intestinal immunity of common carp were affected by diet. Meanwhile, the results show that a mixed diet can promote and improve the immune function of the omnivorous carp intestine, which suggests that paddy fields might be more suitable for the intestinal health and animal welfare of omnivorous fishes because they contain plant and animal diets. Significance and Impact of the Study: As an ecological aquaculture strategy, the rice-fish mode has attracted attention among farmers, researchers and even consumers, especially for the cultivation of common carp in paddy fields. In paddy fields, fish can eat plant-and animal-based diets. However, it is not clear whether common carp feeding on a mixed diet in paddy fields have better intestinal health. This experiment is one of only a few studies performed from the perspective of intestinal micro-organisms and immunity to successfully study the effects of different natural diets on adult common carp. This study also provides a theoretical basis for healthy breeding of common carp in paddy fields.

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“…MiRNAs participate in the regulation of many physiological activities [ 7 ], including development [ 12 , 15 ], immunity [ 18 , 31 ], cell proliferation [ 6 , 54 ], cell apoptosis [ 11 , 41 ], and lipid metabolism [ 40 ], among others. Many studies have investigated the roles of miRNAs in aquatic animals, including Oreochromis niloticus [ 39 ], Oncorhynchus mykiss [ 29 ], Cyprinus carpio [ 27 ], Crassostrea gigas [ 56 ], and Chlamys farreri [ 9 ]. A large number of miRNAs of several aquatic crustaceans, including Daphnia magna [ 42 ], Marsupenaeus japonicus [ 34 ], Litopenaeus vannamei [ 50 ], Eriocheir sinensis [ 14 ], S. paramamosain [ 22 ], and Portunus trituberculatus [ 26 ], have been sequenced and mined.…”

Section: Introductionmentioning

confidence: 99%

Identification and characterization of miRNAs in the gills of the mud crab (Scylla paramamosain) in response to a sudden drop in salinity

et al. 2018

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BackgroundThe mud crab (Scylla paramamosain) is a euryhaline and commercially important species. MiRNAs participate in the regulation of many physiological activities.ResultsThe miRNA transcriptome of the gills of S. paramamosain was used to investigate the expression profiles of miRNAs in response to a sudden drop in salinity. In total, seven known miRNAs and 43 novel miRNAs were identified, with 18 differentially expressed small RNAs. Fourteen thousand nine hundred fifty-one differentially expressed miRNAs target genes were screened by prediction. GO analysis of differentially expressed miRNAs target genes indicated that 578 genes associated with cellular processes, 523 associated with metabolic processes, and 422 associated with single-organism processes were the most strongly affected by a sudden drop in salinity from 23‰ to 3‰. KEGG pathway analysis showed 14 pathways were related to amino acid metabolism, which plays an important role in osmoregulation. Besides, several pathways were associated with starch and sucrose metabolism (ko00500), glycosaminoglycan degradation (ko00531), and galactose metabolism (ko00052).ConclusionsS. paramamosain regulated osmotic pressure and energy balance by regulating target genes to adapt to a sudden changes in salinity. These results provided a basis for further investigations of miRNA-modulating networks underlying the osmoregulation of S. paramamosain.Electronic supplementary materialThe online version of this article (10.1186/s12864-018-4981-6) contains supplementary material, which is available to authorized users.

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Serum immune responses in common carp (Cyprinus carpio L.) to paraquat exposure: The traditional parameters and circulating microRNAs

Cited by 58 publications

References 82 publications

Effects of enzymatic hydrolysates from poultry by‐products (EHPB) as an alternative source of fish meal on growth performance, hepatic proteome and gut microbiota of turbot ( Scophthalmus maximus )

Effects of enzymatic hydrolysates from poultry by‐products (EHPB) as an alternative source of fish meal on growth performance, hepatic proteome and gut microbiota of turbot ( Scophthalmus maximus )

Effects of different diets on the intestinal microbiota and immunity of common carp ( Cyprinus carpio )

Identification and characterization of miRNAs in the gills of the mud crab (Scylla paramamosain) in response to a sudden drop in salinity

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