Serum Inorganic Phosphorus Levels in Males and Females at Progressive Ages, With Concomitant Measurements of Urinary Ketosteroids and Androgens in Men*

Hamilton, James B.; Bunch, Leitha D.; Hirschman, Albert O.

doi:10.1210/jcem-16-4-463

Cited by 15 publications

(3 citation statements)

References 24 publications

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“…Plasma volume increased with age and correlated inversely with erythrocyte ATP levels and PCOz. Recently, a correlation of DPG with age has been noted (25), and may be related t o decreasing concentrations of plasma inorganic phosphate with aging (26). We found an inverse relationship between age and ATP.…”

Section: Discussionsupporting

confidence: 66%

Sickle cell anemia: Erythrokinetics, blood volumes, and a study of possible determinants of severity

Steinberg¹,

Dreiling²

1977

American J Hematol

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The variability in the clinical expression of sickle cell anemia led us to study factors which might influence the course of this disease. We examined erythrokinetics, blood volumes, and variables which influence hemoglobin function in a group of adults with sickle cell anemia of varying degrees of clinical severity. We were unable to correlate any single measurement with the clinical course; however, our patient sample was small and the data suggested areas for further study. An expansion of plasma volume noted in all patients. This made it difficult to predict red cell mass from the hemoglobin level, which consistently underestimated its magnitude. The red cell production index and iron turnover values indicated that there is often a suboptimal erythropoietic response to anemia in sickle cell disease.

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Section: Discussionsupporting

confidence: 66%

Sickle cell anemia: Erythrokinetics, blood volumes, and a study of possible determinants of severity

Steinberg¹,

Dreiling²

1977

American J Hematol

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“…These findings were later supported by Round by means of a longitudinal study, when she also found a significant rise of inorganic phosphorus levels in boys at the onset of puberty (23). In 1955 Hamilton et al studied the relationship between inorganic phosphorus levels and urinary ketosteroids and androgens in men over an extensive age ränge (24). However, they did not find significant correlation between these parameters, although earlier observations indicate that androgens might influence the blood concentration of PJ; in another study Hamilton et al reported that P { levels are elevated in subjects with gonadal dysgenesis, in eunuchoidism, in hypopituitarism and after castration (26).…”

Section: Discussionmentioning

confidence: 99%

“…One of these parameters is alkaline phosphatase catalytic activity (l -4,11 -17). In addition age-related changes for total calcium and inorganic phosphorus have been described earlier (4,19,(21)(22)(23)(24)(25). Due to the accelerated growth in the last decade, these known physiological changes have to be defined for the entire population of adolescents (18).…”

Section: Introductionmentioning

confidence: 98%

Changes of Alkaline Phosphatase, Inorganic Phosphorus and Total Calcium in Sera of 11 to 17 Year Old Healthy Adolescents, and their Relationship to Growth

Widhalm¹,

Hölzl²

1985

Clinical Chemistry and Laboratory Medicine

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Summary:A semi-longitudinal study in 111 healthy school children, 11 years old, was started in May 1976 to evaluate age-related "normal-ranges" of two so-called "routine" tyood parameters during adolescence. Follow-up examinations were performed at one-year intervals until 1982. In this paper growth velocity is described and results of estimations of alkaline phosphatase, inorganic phosphorus (Pj) and total calcium (Ca) are presented and compared with values in the literature.Peak growth velocity in girls (5.94 ± 1.92 cm/year) occurred between 11 and 12 years, in boys (7.73 ± 2.4 cm/year) between the age of 12 and 13 years; from the age of 14 years onwards boys were significantly taller than girls. A strong relationship (p < 0.05) between growth and alkaline phosphatase could be shown throughout the period observed. Alkaline phosphatase activity varied within a wide ränge and reached mean peak values at the age of 11 years in girls (470.9 + 114.8 U/l) and the age of 13 in boys (514.4 ± 135.7 U/l), Afterwards, alkaline phosphatase activity decreased towards adult levels. Inorganic phosphorus constantly decreased in both boys and girls until the age of 16, while from the age of 16 to 17 years a significant increase could be observed in both sexes. Total calcium values showed a significant increase between 12 and 13 years in boys and between 13 and 14 years in girls; after the age of 14 values decreased significantly in both sexes. Our data strongly support the assumption that the known changes of alkaline phosphatase and Pj are mainly due to growth and pfobably secondarily due to sex hormone changes. Änderungen der alkalischen Phosphatase, des anorganischen Phosphors und des Calciums im Serum gesunder i i-bis 17jähriger Jugendlicher und deren Bezug zum Wachstum

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Massive Cerebral Calcifications Associated With Increased Renal Phosphate Reabsorption

Weisinger¹

1986

Arch Intern Med

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Serum Inorganic Phosphorus Levels in Males and Females at Progressive Ages, With Concomitant Measurements of Urinary Ketosteroids and Androgens in Men*

Cited by 15 publications

References 24 publications

Sickle cell anemia: Erythrokinetics, blood volumes, and a study of possible determinants of severity

Sickle cell anemia: Erythrokinetics, blood volumes, and a study of possible determinants of severity

Changes of Alkaline Phosphatase, Inorganic Phosphorus and Total Calcium in Sera of 11 to 17 Year Old Healthy Adolescents, and their Relationship to Growth

Massive Cerebral Calcifications Associated With Increased Renal Phosphate Reabsorption

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