Abstract:The most clinical scoring of traumatic brain injury patient is Glasgow Coma Scale (GCS) score. Lower GCS score higher IL-6 level and higher morbidity and mortality. Neuroinflammation is one mechanism of secondary brain injury. Selective cyclooxygenase (sCOX-2) inhibitors are drugs commonly used in treatment of postoperative pain but also possess an anti-inflammatory effect. The aim of this study is to determine the role of sCOX-2 inhibitors as inhibitors of inflammatory processes in patients with head injury m… Show more
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