The study aimed to investigate the influence of physiological status on the blood metabolic profile of Berari goats in Vidarbha climatic conditions. Blood samples were collected from 12 healthy pregnant goats 21 days before kidding, on the day of kidding, and 21 days after kidding. The samples were analyzed for non-esterified fatty acid (NEFA), total cholesterol (TC), triglyceride (TG), glucose (Glu), total protein (TP), albumin (Alb), globulin (Glb), alanine transaminase (ALT), aspartate transaminase (AST), calcium (Ca) and phosphorous (P). The transition period had significant effect on TG (26.71 ± 2.52a, 17.05 ± 1.90b, 20.83 ± 1.66ab mg/dl), TP (6.13 ± 0.23b, 6.57 ± 0.35b, 8.22 ± 0.29a g/dl), globulin (1.48 ± 0.30b, 1.67 ± 0.34b, 3.69 ± 0.32a g/dl), glucose (66.78 ± 3.30b, 183.47 ± 32.65a, 81.41 ± 6.60b mg/dl) and phosphorus (8.96 ± 0.67a, 5.38 ± 0.79b, 6.59 ± 0.29b mg/dl). The study indicates that the Berari goats were not under metabolic stress and were well-adapted to the tropical and arid climatic conditions of the region. The higher glucose level observed during kidding suggests that the animals were in positive energy status and well-managed during the transition period.