Serum Levels of Male Oligospermia Glycoconjugate Inhibin B Hormone and A - L - Fucose in Kurdistani ( Iraq ) Populations

Ahmed, Govand Ali; Hasan, Hamid G.; Rashid, Aso Omer

doi:10.5742/mejim.2011.55149

Cited by 4 publications

(3 citation statements)

References 45 publications

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“…Furthermore, since it has been suggested that serum inhibin B in relation to male and female reproductive health have been published internationally and the risk of leukemia that may spread to other organs like ovary (Ahmed et al, 2001;Wen et al, 2006;Lee et al, 2008;Moos et al, 2009;Taflan et al, 2011;Dillon and Gracia, 2012), the present study attempt to clarify the correlation between inhibin and serum protein, glutathione and the two vitamins E and C in patients with ALL, the results were reanalyzed by using linear regression analysis, Table 2.…”

Section: Discussionmentioning

confidence: 99%

Correlation of Inhibin and Several Antioxidants in Children with Acute Lymphoblastic Leukemia

Mehde¹,

Mehdi²,

Zainulabdeen³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: Acute lymphoblastic leukemia (ALL) is most common in childhood. Inhibin (a non-steroidal glycoprotein hormone of gonadal origin) can be used as marker of fertility. The current study was conducted to evaluate inhibin levels in ALL patients and to estimate its correlation with some antioxidants in these in comparison with control subjects. Materials and Methods: This study was conducted on sixty patients with ALL and thirty children as controls. Fasting blood samples were taken from each subject and analyzed for haemoglobin, serum protein, vitamin E and C, in addition to glutathione and inhibin. Results: The results of the study showed highly significant decreases (p<0.001) in haemoglobin, glutathione and inhibin levels with significant decreases (p<0.05) in serum protein and vitamin E levels for patients group in comparison with controls while there was no significant differences in vitamin C. Moreover, there were significant correlations between inhibin levels and serum protein, glutathione and both vitamins (E and C) in the ALL patient group (r= 0.81, 0.80, 0.77 and 0.69, respectively). Conclusions: The present results indicated infertility in patients with ALL demonstrated by low inhibin level as a consequence of abnormality in anti-oxidative metabolism due to the cancer process. So, it can be suggested the need for routine measurement of inhibin for leukemic patients to estimate the action of hormones of gonadal origin.

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Section: Discussionmentioning

confidence: 99%

Correlation of Inhibin and Several Antioxidants in Children with Acute Lymphoblastic Leukemia

Mehde¹,

Mehdi²,

Zainulabdeen³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…The prevalence of infertility varies widely, being less in developed countries and more in developing countries where limited resources for investigation and treatment are available [4]. Infertility is an important medical and social problem in the world as regards 15% of couples are infertile and 40% are infertile because of male factor infertility and 40% are because of female factor infertility and in the remainder both factors are associated [5].…”

Section: Introductionmentioning

confidence: 99%

Risk Factors and Causes of Male Infertility-A Review

Mahat¹,

Arora²

2016

Biochem Anal Biochem

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Infertility is defined as inability to achieve conception in a period of one year in a couple, despite regular and adequate unprotected sexual intercourse. A male is said to be infertile if he is unable to impregnate his partner after one year of unprotected intercourse. It is an important medical and social problem in the world as regards 15% of couples are infertile and 40% are infertile because of male factor infertility. This review highlights the risk factors and some causes that are responsible for male infertility. The aim of this review is to generate information which could help in the evaluation of male infertility.

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“…The results also showed that low (74.5 mg/kg) and moderate (235.6 mg/kg) of isoflavones produced a significant (p < 0.05) increase in serum AMH levels while high (1046.6 mg/kg) produced a non-significant (p > 0.05) increase in serum AMH levels in post pubertal rats. The increased levels of antimullerian hormone might have been due to the stimulatory effect on the Sertoli cells by isoflavones as shown in an in vivo study by [22].…”

Section: Effect Of Soy Isoflavone Administration On Serum Anti-mullermentioning

confidence: 99%

Effects of Post-Weaning Consumption of Soy Isoflavones on Prepubertal and Postpubertal Serum Levels of Some Reproductive Hormones of Male Wistar Rats

Godfrey¹,

Daniel²,

Sulaiman³

et al. 2017

ARSci

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Chemically, soy contains a group of phytoestrogens called isoflavones, predominantly genistein and daidzein. The aim of the present study was to determine the effects of post weaning consumption of dietary soy isoflavones on prepubertal and postpubertal serum levels of some reproductive hormones of male Wistar rats. The study involved investigating the effects of different doses of isoflavones in the diet. Male rats were weaned on either soy isoflavone free diet or on isoflavone containing diets, formulated by adding increasing amounts of Novasoy, a commercially available isoflavone supplement to the isoflavone free diet to give varying concentrations of isoflavones. Three isoflavone containing diets were used and these had 74.5, 235.6 and 1046.6 mg total isoflavones/kg pelleted diet. These diets represented the isoflavone concentration lower, equal to and more than that found in soy-based infant formulas respectively. The results obtained showed that; administration of low doses soy isoflavones (74.5 mg/kg) produced significant (p < 0.05) increase in serum Antimullerian Hormone levels both in prepubertal and post pubertal rats, when compared to the control groups. Administration of moderate doses of isoflavones (235.6 mg/kg) produced significant (p < 0.05) increase in serum levels of Antimullerian Hormone and Inhibin in both prepubertal and post pubertal rats when compared to the control groups. Administration of high doses of isoflavones (1046.6 mg/kg) produced significant (p < 0.05) increase in serum levels of Inhibin in both prepubertal and post pubertal rats when compared to the control groups. From this study, it was concluded that post-weaning consumption soy isoflavones produced significant changes in How to cite this paper: Godfrey, S., Daniel, E.E., Oluwadare, S.S. and Yovani, B. 12serum Inhibin and Antimullerian Hormone both in prepubertal and post pubertal male Wistar rats and the changes were dose dependent.

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Serum Levels of Male Oligospermia Glycoconjugate Inhibin B Hormone and A - L - Fucose in Kurdistani ( Iraq ) Populations

Cited by 4 publications

References 45 publications

Correlation of Inhibin and Several Antioxidants in Children with Acute Lymphoblastic Leukemia

Correlation of Inhibin and Several Antioxidants in Children with Acute Lymphoblastic Leukemia

Risk Factors and Causes of Male Infertility-A Review

Effects of Post-Weaning Consumption of Soy Isoflavones on Prepubertal and Postpubertal Serum Levels of Some Reproductive Hormones of Male Wistar Rats

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