Serum Lipids and Statin Treatment During Acute Stroke

Lampl, Yair

doi:10.5772/27177

Acute Ischemic Stroke 2012

DOI: 10.5772/27177

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Serum Lipids and Statin Treatment During Acute Stroke

Yair Lampl¹

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2017

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The effect of statins on the organs: similar or contradictory?

Ahmadi

Ghorbanihaghjo

Argani

2017

J Cardiovasc Thorac Res

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Hydroxy-Methyl-Glutaryl-CoA reductase (HMGCR) – the main enzyme of the cholesterol biosynthesis pathway – is mostly inhibited by statins in hepatocytes. In spite of the other tissues, liver utilizes cholesterol in different ways such as the synthesis of bile acids, excretion in to the intestine and synthesis of lipoproteins. Therefore, statins theoretically alter these pathways; although, there have not been such effects. In this review, we aim to show the roles of extra-hepatic tissues, in particular intestine, adipose and cutaneous tissues in providing the cholesterol after reduction of the whole body cholesterol content by statins.

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The effect of statins on the organs: similar or contradictory?

Ahmadi

Ghorbanihaghjo

Argani

2017

J Cardiovasc Thorac Res

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show abstract

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Serum Lipids and Statin Treatment During Acute Stroke

Cited by 1 publication

References 84 publications

The effect of statins on the organs: similar or contradictory?

The effect of statins on the organs: similar or contradictory?

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