Serum Lipoprotein (a) as an independent marker of cardiovascular risk in patients with Essential Hypertension

Abstract

<p><strong>Aim:</strong> Aims of study was to find out the level of serum lipoprotein (a) in healthy and hypertensive subjects and role of serum lipoprotein (a) as an independent marker of cardiovascular risk in patients with essential hypertension.</p><p><strong>Material and Method:</strong> 100 patients with essential hypertension and 50 apparently healthy subjects were included in study. Sera were collected from them and measure serum Lipoprotein(a) with Latex Turbidimetric method on automated chemistry analyzer. Unpaired T-test was used to assess the significant difference in the means of the studied variables in the different groups.</p><p><strong>Results: </strong>The mean level of Serum Lipoprotein(a) is higher in patients with essential hypertension comparing with the control group (21.6 ± 11.9 and 30.3 ± 13.6,p <0.001).</p><p><strong>Conclusion: </strong>The findings clearly project that plasma concentration of Lp(a) albeit within normal range could be an independent risk factor for atherosclerosis and could contribute towards increasing the risk for cardiovascular diseases in persons with essential hypertension.</p