2020
DOI: 10.21521/mw.6134
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Serum malondialdehyde, coenzyme Q10 and 8-hydroxydeoxyguanosine levels in calves with foot-and-mouth disease

Abstract: Foot-and-mouth disease (FMD) is an acute, contagious viral disease in cattle that is associated with enormous economic losses in Turkey and worldwide. The purpose of this study was to determine changes in serum malondialdehyde (MDA), coenzyme Q10 (CoQ10), 8-hydroxydeoxyguanosine (8-OHdG) and deoxyguanosine (dG) and to perform histopathological examinations in calves with FMD. Thirty calves were studied, 20 of which were infected with FMD and 10 were free of the disease. Following a routine clinical examina… Show more

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“…Previously, 8-OHdG levels were measured by HPLC with electrochemical detection (HPLC-EC) [ 70 ]; actually, ELISA kits detecting 8-OHdG are available allowing the use of this biomarker for investigating the OS involvement in many human diseases [ 72 ]. Additionally, in veterinary medicine, 8-OHdG is more and more assessed for evaluating OS-mediated DNA damage in either biotic or abiotic diseases [ 73 , 74 , 75 ].…”
Section: The Oxidative Profile and Its Alteration (Oxidative Stress) ...mentioning
confidence: 99%
“…Previously, 8-OHdG levels were measured by HPLC with electrochemical detection (HPLC-EC) [ 70 ]; actually, ELISA kits detecting 8-OHdG are available allowing the use of this biomarker for investigating the OS involvement in many human diseases [ 72 ]. Additionally, in veterinary medicine, 8-OHdG is more and more assessed for evaluating OS-mediated DNA damage in either biotic or abiotic diseases [ 73 , 74 , 75 ].…”
Section: The Oxidative Profile and Its Alteration (Oxidative Stress) ...mentioning
confidence: 99%