Serum selenium in children with acute lymphoblastic leukemia: Preliminary results

Sampling, storing, sample pretreatment, and experimental conditions for selenium (Se) determination in human serum, plasma, and whole blood by X-ray emission spectrometric (XRS) methods are described. Concentration levels in these biological fluids, found by this technique, are discussed and compared to values found by other techniques for the same healthy population group in the same area. XRS analysis of blood from patients with various pathological conditions is reviewed, with special attention to the relation of Se with the concentration level of other essential or nonessential trace elements.

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Determination of selenium in blood components by X-ray emission spectrometry

Robberecht

Deelstra

Grieken

1990

Biol Trace Elem Res

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Serum selenium levels in multinodular goitre

Samir

El-Awady

1998

Clin Otolaryngol

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Serum selenium levels were measured in 22 patients with a multinodular goitre and compared to 15 normal controls using atomic absorption spectrophotometry. The serum selenium was significantly low in these patients (patients' mean = 9.6 +/- 1.24 mcg/l, versus control mean = 11.7 +/- 1.64 mcg/l and P < 0.005). Serum T4 and T3 were within the normal range in all patients and controls. Their levels correlated positively, though weakly, with the serum selenium levels (r = 0.4 and 0.36, respectively). The control selenium levels in this study were lower than the reported figures from some European countries, but they were close to those from other studies in Egypt. It seems that Egypt is a low selenium area. A wide-scale epidemiological study is recommended, together with the examination of the possible preventive role of selenium supplementation in areas of endemic goitre.

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Serum selenium in children with acute lymphoblastic leukemia: Preliminary results

Cited by 2 publications

References 23 publications

Determination of selenium in blood components by X-ray emission spectrometry

Determination of selenium in blood components by X-ray emission spectrometry

Serum selenium levels in multinodular goitre

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