Serum Selenium Level in Healthy Koreans

Kim, Young-Jae; Galindev, Oyunbileg; Sei, Jun Han; Bae, Seog Nyeon; Im, Hosub; Wen, Li; Seo, Young Rok; Ahn, Woong Shick

doi:10.1007/s12011-009-8353-6

Cited by 18 publications

(12 citation statements)

References 22 publications

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“…Se levels were significantly higher in the rural group than the urban group (97±36 and 87±31 μg/L, respectively). Values obtained compare with those obtained by Al-Sayer et al and Young-Jae et al for adult residents in Kuwait and Korea, respectively [54,55]. Differences according to geographic location were significant.…”

Section: Discussionsupporting

confidence: 78%

Serum Levels of Cu, Se, and Zn in Adult Rural/Urban Residents in Ghana: Paradigm Shift?

Asare

Nani

2009

Biol Trace Elem Res

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Deficiencies in Cu, Se, and Zn impair one or more biochemical functions, and excess are associated with toxicity. Baseline studies on the Ghanaian population are scanty. The study was undertaken to determine whether significant rural/urban differences in the serum levels of Cu, Se, and Zn did exist. Forty males/60 females from rural and 50 males/50 females from urban Ghanaian communities were sampled. Serum Cu, Se, and Zn were determined using flame atomic absorption spectrometry. Cu level for rural and urban subjects was 997 +/- 333 and 979 +/- 290 microg/L, respectively (p = 0.68). However, Cu levels were significantly higher in the rural females (1,063 +/- 367 microg/L) than the rural males (898 +/- 249 microg/L; p = 0.0085). Se levels for rural/urban subjects were 97 +/- 36 and 87 +/- 31 microg/L, respectively (p = 0.03). Zn levels in the rural/urban subjects were 312 +/- 218 and 150 +/- 102 microg/L, respectively (p = 0.002). Additionally, Zn was significantly higher in rural females (428 +/- 204 microg/L) than the urban females (166 +/- 103 microg/L; p = 0.0002). Finally, Zn was significantly higher in rural females (428 +/- 204 microg/L) than males (172 +/- 116 microg/L; p = 0.0028). In conclusion, Cu, Se, and Zn were higher in the rural group compared to the urban group, and the generally low Zn levels were confirmed in another cohort follow-up study.

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Section: Discussionsupporting

confidence: 78%

Serum Levels of Cu, Se, and Zn in Adult Rural/Urban Residents in Ghana: Paradigm Shift?

Asare

Nani

2009

Biol Trace Elem Res

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“…The mean serum selenium level in healthy Korean subject was 112.05±30.42 μg/L, which was higher than that for healthy European adults 38–40. Similar to the general population, Korean patients with IBD showed higher mean levels of serum selenium compared with Caucasians 20.…”

Section: Discussionmentioning

confidence: 59%

Risk Factors for Vitamin D, Zinc, and Selenium Deficiencies in Korean Patients with Inflammatory Bowel Disease

et al. 2017

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Background/AimsStudies on the micronutrient status of Asian patients with inflammatory bowel disease (IBD) are scarce. We evaluated the prevalence of micronutrient deficiency and verified the risk factors for micronutrient deficiency in Korean patients with IBD.MethodsWe measured the serum levels of 25-hydroxyvitamin D3 [25-(OH)D], zinc, and selenium to analyze the clinical risk factors for micronutrient levels below the reference values. In addition, we compared the 25-(OH)D levels of patients with IBD to those of age- and sex-matched healthy controls.ResultsAmong the 83 patients, 74 (89.2%) had suboptimal serum 25-(OH)D levels. The mean plasma 25-(OH)D level in patients with IBD was significantly reduced compared to that of the healthy controls (12.3±6.2 ng/mL vs 20.0±6.7 ng/mL; p<0.001). The proportions of patients with lower serum zinc and selenium levels were 39.0% and 30.9%, respectively. Female sex (p=0.012) and Crohn’s disease (p=0.012) were associated with vitamin D deficiency. Patients younger than 40 years were at increased risk for zinc deficiency (p=0.045). Female sex (p=0.015) and low serum albumin level (<3.3 g/dL) (p=0.047) were risk factors for selenium deficiency.ConclusionsMany Korean patients with IBD have vitamin D, zinc, and selenium deficiencies, suggesting the necessity for monitoring levels of these micronutrients.

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“…Possible explanations for the partially discrepant findings in our and some prior studies include differences in the underlying populations (e.g., Asian vs. European), differences in the outcome definitions (e.g., NAFLD definition based on CT liver fat accumulation and alcohol consumption vs. MRI‐derived FLD), differences in the statistical methodology used (implicit assumption of linear relation between biomarker and outcome vs. estimation of nonlinear associations by means of restricted cubic splines in the present study), and different selenium status in the study populations. Interestingly, as reported by Hurst and colleagues , while SELENOP is a sensitive biomarker for selenium status at low‐to‐moderate selenium intakes (as in Germany) , it is a less useful biomarker in populations with higher selenium intake (such as Korea and Japan), where it may approach or even attain its maximum concentration .…”

Section: Discussionmentioning

confidence: 89%

Circulating selenoprotein P levels in relation to MRI‐derived body fat volumes, liver fat content, and metabolic disorders

Giuseppe

Koch

Schlesinger

et al. 2017

Obesity

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Serum Selenium Level in Healthy Koreans

Cited by 18 publications

References 22 publications

Serum Levels of Cu, Se, and Zn in Adult Rural/Urban Residents in Ghana: Paradigm Shift?

Serum Levels of Cu, Se, and Zn in Adult Rural/Urban Residents in Ghana: Paradigm Shift?

Risk Factors for Vitamin D, Zinc, and Selenium Deficiencies in Korean Patients with Inflammatory Bowel Disease

Circulating selenoprotein P levels in relation to MRI‐derived body fat volumes, liver fat content, and metabolic disorders

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