Serum total IgE, ascaris lumbricoides specific IgE and eosinophils in parasites-infected children in a tropical area

Sales, Valéria Soraya de Farias; Silva, Edna Marques Araújo; Medeiros, Sarah Dantas Viana; Souza, Luanda Barbara Ferreira Canário de; Silva, Vanessa Marques Araújo; Brito, Tereza Neuma de Souza; Machado, Paula Renata Lima

doi:10.1186/1939-4551-8-s1-a223

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“…Eosinophilia was significantly more frequent among children infected with Ascaris lumbricoides, Evermicularis, and H nana. Similar observations were reported by other studies 28,[34][35][36][37] .This could be explained by presence of tissue-invading larvae that migrate from the small intestine into blood circulation to reach lungs and elicit pulmonary inflammation 4, 38-40 . Nevertheless, eosinophilia was non-significant among schoolchildren infected with Trichuris trichiura and Taeniasaginata.…”

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confidence: 81%

Prevalence of Intestinal Helminthiasis and Their Association With Eosinophilia Among Schoolchildren in Wadidhahar District at Sana’a Governorate, Yemen

Othman

Al-Mekhalfi

2020

Univ J Pharm Res

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Objectives: Allergy and parasitic infections are common causes of blood eosinophilia. Intestinal helminthiasis remains a major health problem in many developing countries. Eosinophils are an effector immune cell against parasites.The objective of this study was to determine the prevalence of intestinal helminthiasis and eosinophilia among primary schoolchildren in WadiDhahr district, Sana’a governorate, Yemen. Subjects and methods: Four hundred and fourteen pupils were enrolled in this study. Blood and stool samples were collected from each pupil. Stool samples were examined using Hoffman’s sedimentation method for the presence of worms’ ova.Blood smears were stained with Giemsa stain and used for counting the eosinophils’ percentages. Results: Out of 414 specimens, the prevalence of intestinal helminths infections was 79(19%) among schoolchildren; (52 (18%) males and 27 (21%) females). Eosinophilia was 134 (32%) observed in the participated pupils; 86 (30%) males and 48 (37%) females. The age group 5-10 years had the highest frequent rate of eosinophilia with a statistically significant difference (χ2 = 10.4, P = 0.002) and 60% of infected students with intestinal worms had eosinophilia (χ2 = 32.8, P< 0.001). Females had a higher rate of eosinophilia than males. The most common helminthiasis infections were hymenolepiasis (10.6%) followed by ascariasis (4.1%), enterobiasis (2.7%), and taeniasis (2.4%). The high rate of eosinophilia was recorded among students infected with Ascaris lumbricoides (82%) followed by Enterobius vermicularis (73%), Trichuristrichiura(67%), Hymenolepis nana (59%), and Taeniasaginata (30%). Conclusions: Intestinal helminthiasis still a common health problem among schoolchildrenin WadiDhahar district at Sana’a governorate, Yemen, and was found to be associated with high blood eosinophils. Eosinophilia was statistically significant among students infected with ascariasis, hymenolepiasis, and enterobiasis but not with taeniasis and trichuriasis. Peer Review History: Received 12 July 2020; Revised 14 August; Accepted 27 August, Available online 15 September 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Dr. Wadhah Hassan Edrees Affiliation: Hajjah University, Yemen E-mail: edress2020@gmail.com Name: Omnia Momtaz Al-Fakharany Affiliation: E-mail: amina.elfakharany@pharm.tanta.edu.eg Comments of reviewer(s): Similar Articles: FREQUENCY OF INTESTINAL PARASITIC INFECTIONS AMONG SCHOOLCHILDREN IN IBB CITY-YEMEN PREVALENCE AND CAUSES OF TRAUMATIC DENTAL INJURIES TO ANTERIOR TEETH AMONG PRIMARY SCHOOL CHILDREN IN SANA'A CITY, YEMEN

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