Serum Transaminase Activity in Uncomplicated and Complicated Pregnancy and in Newborns

Borglin, N. E.

doi:10.1210/jcem-18-8-872

Cited by 42 publications

(27 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PET and eclampsia are pregnancy related complications with mortality rate less thean 1% 8 . And abormal liver function occurs in 20-30% of pregnancies complicated by PET and eclampsia 3,4 and are associated with poor maternal and fetal outcome 3 .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Alteration of Liver Function in Preeclampsia and Eclampsia

Bhowmik

Akhtari

Kumar

et al. 2013

Chatt Maa Shi Hosp Med Coll J

View full text Add to dashboard Cite

Introduction: Abnormal liver function in patients with PET and eclampsia affect both maternal and fetal outcome negatively. This study was done to see change of liver function in comparison to normal pregnancy and normal reference value. Methods: Consecutive 47 patients of PET and eclampsia were taken as cases and 35 normal expectant mother were enrolled as controls. ALT, AST, alkaline phosphatase, serum bilirubin, serum creatinine and urine for albumin of patients andnormal pregnant women were tested and compared. Results: ALT, AST, S. Bilirubin, Alkaline phoshatase levels were elevated with more proteinuria among patients with PET and eclampsia, but ALT and alkaline phosphatase levels and level of proteinuria were significantly higher. Conclusions: Liver function impairment is very common in pre-eclampsia and eclampsia.

show abstract

Section: Discussionmentioning

confidence: 99%

“…These are pregnancy specific hypertensive syndrome, when severe, can cause substantial maternal and fetal mortality and morbidity 2 . Prevalence of abnormal liver function tests in pregnancy complicated by PET and eclampsia varies from 20 -30 % 3,4 . Pathophysiology of PET and eclampsia is not clearly known.…”

Section: Introductionmentioning

confidence: 99%

Alteration of Liver Function in Preeclampsia and Eclampsia

Bhowmik

Akhtari

Kumar

et al. 2013

Chatt Maa Shi Hosp Med Coll J

View full text Add to dashboard Cite

show abstract

“…He also found a definite in crease in six out of seven cases of accidental haemorrhage. Borglin (1958) found elevations of serum glutamic-oxalacetic transaminase in one-third of his cases of pre-eclamptic toxaemia, but was un able to correlate this with the clincal condition. We have chosen serum isocitric dehydrogenase because the placenta is a rich source of this soluble enzyme, normal serum contains only traces and elevations are found in only a few diseases, principally those with necrosis of liver cells (Sterkel, Spencer, Wolfson and Williams-Ashman, 1958;Kerpola, Nikkila and Pitkanen, 1959).…”

mentioning

confidence: 85%

Serum Isocitric Dehydrogenase in Normal Pregnancy and Pre-Eclamptic Toxaemia

Dawkins¹,

Wigglesworth²

1961

Pathobiology

View full text Add to dashboard Cite

“…9 In HELLP syndrome, an elevation in liver function test results is noted. 10 Periportal hemorrhagic necrosis in the periphery of the liver lobule is Liver Function Test (LFT) abnormalities occur in 3% of the pregnancies, and probably the lesion that causes elevated serum liver enzymes.…”

Section: Medical Conditionsmentioning

confidence: 99%

Study of liver function tests in hypertensive disorders of pregnancy

Pusuloori¹,

Arora²

2018

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Hypertensive disorders of pregnancy with spectrum complications is one among leading causes of feto-maternal morbidity and mortality especially when its associated with HELLP syndrome.Methods: The present prospective study was conducted over a period of three years in the department of obstetrics and gynecology at Chalmeda Anandarao Institute of Medical Sciences, Karimnagar, Telangana from January 2008 to January 2009. This is a prospective study on 50 pregnant women with 28-40 weeks of gestation with diastolic BP ≥110 mm Hg recorded 6 hours apart.Results: This is a prospective study on 50 pregnant women with 28-40 weeks of gestation with diastolic BP≥110 mm Hg recorded 6 hours apart. Severe pre eclampsia was seen in younger age group ˂25 years. In patients with raised LFTs unbooked cases were more (64%) showing complications are more in unbooked cases. Renal complications are seen in 16% of the total cases and in 28% of the cases with raised LFTs. In overall study group number of primi gravid were 50% and multi were 27%. Incidence of severe pre eclampsia was 78% in overall cases. In patients with raised LFTs the incidence was 30 (88%).Conclusions: Detection of increased LFTs in cases of severe pre-eclampsia is a risk category, associated with increased rate of feto-maternal complications, compared to severe pre-eclampsia with normal LFTs. Such cases need special attention with early detection and referral to higher centre with better facilities of NICU set up to reduce the complications and mortality.

show abstract

Serum Transaminase Activity in Uncomplicated and Complicated Pregnancy and in Newborns

Cited by 42 publications

References 0 publications

Alteration of Liver Function in Preeclampsia and Eclampsia

Alteration of Liver Function in Preeclampsia and Eclampsia

Serum Isocitric Dehydrogenase in Normal Pregnancy and Pre-Eclamptic Toxaemia

Study of liver function tests in hypertensive disorders of pregnancy

Contact Info

Product

Resources

About