Serum Urate Concentrations in Male High-School Students

Kasl, Stanislav V.

doi:10.1001/jama.1966.03110200069020

Cited by 36 publications

(11 citation statements)

References 10 publications

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“…Stetten and Hearon [17] reported a positive and significant correlation (r = 0.07) between serum uric acid level and the score of an intelligence test. Other studies [4,12,3,11,1] reported that serum or plasma uric acid level was higher in executives or Ph.D. than craftsmen or general population, in highschool students who engaged in extracurricular activities more often than those who did less so, in students with a higher educational level than those with a lower level, and in those with higher score or degree of drive, activity, leadership or achievements than those with a lower score.…”

Section: Introductionmentioning

confidence: 95%

Blood Uric Acid Level and IQ: A Study in Twin Families

Inouye

Asaka

1984

Acta genet. med. gemellol.: twin res.

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Applying newly devised model, heritability (VA/VP) of plasma uric acid level, corrected for age and sex and standardized, was estimated at 0.8 in families consisting of twin parents, spouses and children. Correlation between spouses due to common genotype (ρ) was approximately 0.1, and variance due to common familial environment (VEC/Vp) was -0.3. Analysis of families of selected twin children and their parents resulted in two estimates of heritability: approximately 0.7 and 0.3, ρ being 0.34 and 0.04, and VEC/Vp being 0.04 and 0.34, respectively. Regression of IQ (y) on corrected and standardized plasma uric acid level (x) in the twin children was y = 5.56x + 123, correlation being 0.334 (p < 0.025). The result indicates a genetic basis of blood uric acid level, which may have resulted from polymorphisms in purine metabolism pathway, end product of which is uric acid in man. The significant correlation between plasma uric acid level and IQ suggests a contribution of partly common gene loci to the two quantitative traits.

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Section: Introductionmentioning

confidence: 95%

Blood Uric Acid Level and IQ: A Study in Twin Families

Inouye

Asaka

1984

Acta genet. med. gemellol.: twin res.

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“…"achievement oriented behaviour" and may even act as an "endogenous cortical stimulant" (Brooks and Mueller, 1966;Kasl, Brooks, and Cobb, 1966).…”

mentioning

confidence: 99%

Relation of serum uric acid to body bulk, haemoglobin, and alcohol intake in two South Pacific Polynesian populations.

Evans¹,

Prior²,

Harvey³

1968

Annals of the Rheumatic Diseases

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“…2. If we take as a result of this study the renewed confirmation (Kasl, Brooks, & Cobb, 1966;) that serum urate levels seem related to indirect measures of achievement striving, while selfreport measures of actual achievement do not seem to correlate in a reliable fashion, then the question still remains what the implica- It seems to us that these results are fully consistent with Orowan's (1955) notion of uric acid as a stimulant of central nervous system functioning, that is, an activating agent. According to Orowan's view, uric acid would affect a person's general, nonspecific level of activation, making that person more alert, striving, and active.…”

Section: Uric Acid and Achievementmentioning

confidence: 65%

Uric acid and achievement.

Mueller¹,

French²

1974

Journal of Personality and Social Psychology

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The purpose of the present study was (a) to replicate our previous finding that serum uric acid correlated .66 with achievement-oriented behavior, (6) to relate serum uric acid to achievement motivation, and (c) to relate serum uric acid to actual achievement. Data on 114 male university professors included serum uric acid measured by the auto-analyzer method, achievementoriented behavior rated from semiformal interviews, Atkinson's measure of need for achievement, Heckhausen's Thematic Apperception Test measure of hope for success, and rate of promotion and number of publications as measures of actual achievement. The findings were the following: (a) Serum uric acid correlated .50 with achievement-oriented behavior, and the validity of achievement-oriented behavior was indicated by correlations of .24 and .29 with actual achievement, (b) Neither measure of achievement motivation correlated with serum uric acid in the total sample, (c) Serum uric acid was not related to either measure of actual achievement.

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Serum Urate Concentrations in Male High-School Students

Cited by 36 publications

References 10 publications

Blood Uric Acid Level and IQ: A Study in Twin Families

Blood Uric Acid Level and IQ: A Study in Twin Families

Relation of serum uric acid to body bulk, haemoglobin, and alcohol intake in two South Pacific Polynesian populations.

Uric acid and achievement.

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