2017
DOI: 10.1016/j.ijcard.2016.12.183
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Serum uromodulin is a predictive biomarker for cardiovascular events and overall mortality in coronary patients

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Cited by 45 publications
(47 citation statements)
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“…Value of the data No prospective data on the power of the ratio between serum creatinine and serum uromodulin to predict cardiovascular events were available at present. This data article further proves the association of the creatinine to uromodulin ratio in serum samples with future cardiovascular events as described in the main article [1] by providing additional cox regression models. Whereas the main article [1] has evaluated the performance of uromodulin as a biomarker to predict mortality, this data article contains the c-statistics-based evaluation of the creatinine to uromodulin ratio to predict cardiovascular events and major cardiovascular events.…”
supporting
confidence: 67%
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“…Value of the data No prospective data on the power of the ratio between serum creatinine and serum uromodulin to predict cardiovascular events were available at present. This data article further proves the association of the creatinine to uromodulin ratio in serum samples with future cardiovascular events as described in the main article [1] by providing additional cox regression models. Whereas the main article [1] has evaluated the performance of uromodulin as a biomarker to predict mortality, this data article contains the c-statistics-based evaluation of the creatinine to uromodulin ratio to predict cardiovascular events and major cardiovascular events.…”
supporting
confidence: 67%
“… This data article further proves the association of the creatinine to uromodulin ratio in serum samples with future cardiovascular events as described in the main article [1] by providing additional cox regression models. Whereas the main article [1] has evaluated the performance of uromodulin as a biomarker to predict mortality, this data article contains the c-statistics-based evaluation of the creatinine to uromodulin ratio to predict cardiovascular events and major cardiovascular events. This data article helps researchers to evaluate the potential of creatinine to uromodulin ratio as a biomarker.…”
supporting
confidence: 67%
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“…In the past decade, several genome-wide association studies have identified common variants in the promoter region of the UMOD gene as risk factors for progression to CKD and hypertension [6][7][8][9]. It has also been reported that the serum uromodulin concentration correlates with mortality in patients with cardiovascular disease [10,11]. Moreover, the findings of in vivo studies in an experimental mouse model lacking the uromodulin gene suggest that uromodulin has a renoprotective effect [12,13].…”
Section: Introductionmentioning
confidence: 99%