Serum vitamin A in protein—calorie malnutrition

Zaklama, Mona S.; Gabr, Mohamed; El-Maraghy, S; Patwardhan, V. N.

doi:10.1093/ajcn/26.11.1202

Cited by 11 publications

(2 citation statements)

References 17 publications

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“…Vitamin A deficient children treated with an augmented dietary protein intake demonstrated an increase in serum protein markers as well as serum retinol levels [8]. In this extreme clinical scenario, retinol deficiency was successfully managed through this dietary intervention alone, without the addition of vitamin A rich foods or vitamin A supplementation [9].…”

Section: Discussionmentioning

confidence: 99%

Vitamin A Deficiency after Gastric Bypass Surgery: An Underreported Postoperative Complication

et al. 2011

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Introduction. Few data are available on vitamin A deficiency in the gastric bypass population. Methods. We performed a retrospective chart review of gastric bypass patients (n = 69, 74% female). The relationship between serum vitamin A concentration and markers of protein metabolism at 6-weeks and 1-year post-operative were assessed. Results. The average weight loss at 6-weeks and 1-year following surgery was 20.1 ± 9.1 kg and 44.1 ± 17.1 kg, respectively. At 6 weeks and 1 year after surgery, 35% and 18% of patients were vitamin A deficient, (<325 mcg/L). Similarly, 34% and 19% had low pre-albumin levels (<18 mg/dL), at these time intervals. Vitamin A directly correlated with pre-albumin levels at 6 weeks (r = 0.67, P < 0.001) and 1-year (r = 0.67, P < 0.0001). There was no correlation between the roux limb length measurement and pre-albumin or vitamin A serum concentrations at these post-operative follow-ups. Vitamin A levels and markers of liver function testing were also unrelated. Conclusion. Vitamin A deficiency is common after bariatric surgery and is associated with a low serum concentration of pre-albumin. This fat-soluble vitamin should be measured in patients who have undergone gastric bypass surgery and deficiency should be suspected in those with evidence of protein-calorie malnutrition.

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Section: Discussionmentioning

confidence: 99%

Vitamin A Deficiency after Gastric Bypass Surgery: An Underreported Postoperative Complication

et al. 2011

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“…Though few other groups have presented their data in the same way as Golden, many other studies also recorded children’s plasma albumin concentrations when they presented with kwashiorkor and marasmus, 18 – 29 or when those with kwashiorkor were given appropriate dietary treatment, 19 , 22 , 24 , 30 – 36 in some cases whilst also comparing the efficacy of different milk formulas. 33 – 36 Many of these studies were designed to elucidate the roles of other specific elements, such as vitamin deficiencies, but also included the albumin data, either as a list, a statistical parameter, or a plot, which allowed me to present them in a common graphic format in Figure 3 .…”

Section: What Do Other Studies Of Albumin Levels In Kwashiorkor Show?mentioning

confidence: 99%

Oedema in kwashiorkor is caused by hypoalbuminaemia

Coulthard

2014

Paediatrics and International Child Health

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It has been argued that the oedema of kwashiorkor is not caused by hypoalbuminaemia because the oedema disappears with dietary treatment before the plasma albumin concentration rises. Reanalysis of this evidence and a review of the literature demonstrates that this was a mistaken conclusion and that the oedema is linked to hypoalbuminaemia. This misconception has influenced the recommendations for treating children with severe acute malnutrition. There are close pathophysiological parallels between kwashiorkor and Finnish congenital nephrotic syndrome (CNS) pre-nephrectomy; both develop protein-energy malnutrition and hypoalbuminaemia, which predisposes them to intravascular hypovolaemia with consequent sodium and water retention, and makes them highly vulnerable to develop hypovolaemic shock with diarrhoea. In CNS this is successfully treated with intravenous albumin boluses. By contrast, the WHO advise the cautious administration of hypotonic intravenous fluids in kwashiorkor with shock, which has about a 50% mortality. It is time to trial intravenous bolus albumin for the treatment of children with kwashiorkor and shock.

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Nutritional Factors in Corneal Xerophthalmia and Keratomalacia

Muhilal¹

1982

Archives of Ophthalmology

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Six measures of nutritional status ation and "keratomalacia" remains SUBJECTS AND METHODS were studied in 162 consecutive cases of less certain. As already described (p 404),3162 conse presumed nutritional keratopathy rarging from mild xerosis through full-thickness See also p 404. cutive patients with corneal xerophthal mia or keratomalacia seen at the Cicendo necrosis (keratomalacia) and In a variety (Indonesia) Eye Hospital between June of control subjects. The severity of cor-Reports of corneal destruction are 1977 and September 1978 underwent nealInvolvement was related to the sever-almost entirely limited to malnoudetailed ophthalmic, pediatric, and bacte , Iltll. ,8 Complete corneal necrosis: bilat-12 stt to Wil n (T() 0hth iah Inslituht,, 61110 N Wolfe St, ialtimore, NID 21205 I[}r D t by most severe lesion in worst lft -trint reu sS ttlt g i a l era l Sttnterl..Classified eye (p 404).

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Serum vitamin A in protein—calorie malnutrition

Cited by 11 publications

References 17 publications

Vitamin A Deficiency after Gastric Bypass Surgery: An Underreported Postoperative Complication

Vitamin A Deficiency after Gastric Bypass Surgery: An Underreported Postoperative Complication

Oedema in kwashiorkor is caused by hypoalbuminaemia

Nutritional Factors in Corneal Xerophthalmia and Keratomalacia

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