Serum Zinc and Copper Levels in Healthy Japanese Infants

Ohtake, Masakazu

doi:10.1620/tjem.123.265

Cited by 29 publications

(7 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mean zinc concentrations in the serum of our infants were similar to those that have been reported for breast-fed infants (29,40) or lower (41). Our results are also similar (42,43) or lower (44)(45)(46) than those reported for infants on mixed feeding. According to Prasad, the serum zinc concentration is at its lowest at the age of 3 months and rises to levels within the adult reference range by 4 months (47).…”

Section: Discussionsupporting

confidence: 89%

“…According to Prasad, the serum zinc concentration is at its lowest at the age of 3 months and rises to levels within the adult reference range by 4 months (47). However, mean levels lower than those seen in adults have been observed at ages 6-12 months (43,44,46). At ages 4-9 months, about one-third of our infants had a serum concentration below the lower reference limit for adults, and their serum concentrations correlated with zinc intake.…”

Section: Discussioncontrasting

confidence: 45%

See 1 more Smart Citation

Low Zinc Intake During Exclusive Breast‐Feeding Does Not Impair Growth

Salmenperä,

Perheentupa,

Näntö

et al. 1994

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

We studied zinc nutrition in exclusively breast‐fed infants whose growth deviated from the norm. Their number fell from 200 at birth to 116 at the age of 6 months and 36 at the age of 9 months. The mothers received 0, 20, or 40 mg Zn+ + as sulfate daily. Breast milk intake and concentrations of zinc in milk as well as in maternal and infant serum were measured. Individual zinc concentrations in milk showed channeling. The 20‐mg supplement had no effect on the parameters measured. In contrast, 40 mg increased the maternal serum zinc concentration by 2 months and slowed the normal decline of milk zinc concentration by 6 months. Maternal supplementation had no effect on infant serum concen‐trations; they remained lower than adult levels throughout the 1st year of life. Zinc intake was low (about one‐tenth of RDA), but it seemed to be adequate; the serum concentrations of the infants were stable after the age of 2 months. Low zinc concentrations in serum were not associated with impaired growth. On the contrary, the infants with the highest rates of growth had the lowest zinc concentrations. The infant serum zinc concentrations were channeled, but they were also influenced by the zinc intake. Reference values for breast‐fed infants are given.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussioncontrasting

confidence: 45%

Low Zinc Intake During Exclusive Breast‐Feeding Does Not Impair Growth

Salmenperä,

Perheentupa,

Näntö

et al. 1994

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

show abstract

“…Serum copper levels during early infancy, however, have been reported to be lower than those of adults (Henkin et al 1973;Ohtake 1977), and it has not been clear whether the low serum or plasma zinc levels of infants reported in the United States (Henkin et al 1973;Walravens and Hambidge 1976), and in Japan (Ohtake 1977) are a normal physiological variation at this age, or they are the result of suboptimal zinc nutrition.…”

mentioning

confidence: 99%

Zinc and copper concentrations in human milk and in serum from exclusively-breast-fed infants during the first 3 months of life.

Ohtake

Chiba

Mochizuki

et al. 1981

Tohoku J. Exp. Med.

Self Cite

View full text Add to dashboard Cite

“…Th e copper conte nt of Jap an ese formula milk was 0.05 mg/L (15,20), onl y one -fifth that of bre ast milk and lower than the value recommended by the FAa/WHO (0.4 mg/L) (23) and European Society for Pediat ric Gastroenterology and Nutrition (E SPGN) (24). Ohtake reported that se rum cop per levels in BF infant s were high er th an in FF infan ts at 1 month of age (13). Ho wever, our studies show ed no statistically significant difference in plasma copper con centration s bet we en BF and F F infants.…”

Section: Discussionmentioning

confidence: 41%

“…The y play important role s as components of many enzy mes and the catalysts of enz yme sys tems (1,2). Alth ough their levels in plasma, er ythrocytes, and hair in infant s have been repo rted (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13), few reports are available on their levels in relation to dietar y intake (14)(15)(16)(17)(18). Hum an breast milk is kno wn to be the best natural source of nutri ents for infants.…”

mentioning

confidence: 99%

Trace Elements (Copper, Zinc, Manganese, and Selenium) in Plasma and Erythrocytes in Relation to Dietary Intake During Infancy

Hatano,

Aihara,

Nishi

et al. 1985

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

All determinations of copper, zinc, manganese, and selenium were performed with a flameless atomic absorption spectrophotometer. Seventy‐three full‐term infants aged 1 to 52 weeks were divided into three age groups. Each age group contained two subgroups, breast‐fed and formula‐fed. No statistically significant differences between formula‐fed and breast‐fed subgroups were found in regard to the levels of copper and zinc in plasma and erythrocytes. At 1 to 5 weeks of age, the manganese concentration of erythrocytes was higher in formula‐fed than in breast‐fed infants (p < 0.001). This might be due to the high dietary intake of this element in the formula‐fed subgroup. On the other hand, plasma selenium concentrations were significantly higher in breastfed than in formula‐fed infants of all ages (p < 0.01 at 1 to 5 weeks and p < 0.05 at 6 to 52 weeks). This suggests that selenium compounds are biologically more available for infant nutrition in breast milk than in formula.

show abstract

Serum Zinc and Copper Levels in Healthy Japanese Infants

Cited by 29 publications

References 17 publications

Low Zinc Intake During Exclusive Breast‐Feeding Does Not Impair Growth

Low Zinc Intake During Exclusive Breast‐Feeding Does Not Impair Growth

Zinc and copper concentrations in human milk and in serum from exclusively-breast-fed infants during the first 3 months of life.

Trace Elements (Copper, Zinc, Manganese, and Selenium) in Plasma and Erythrocytes in Relation to Dietary Intake During Infancy

Contact Info

Product

Resources

About