“…The extraction of mandibular third molars is one of the common oral surgeries, and it is usually performed under local anesthesia and nitric oxide anesthesia 3) . In recent years, the intravenous sedation technique has rapidly developed, and it is currently a commonly applied anesthesia technique in oral surgery 17) . However, compared to several studies on surgery with traditional local anesthesia and nitric oxide anesthesia, few studies have investigated the effects and advantages of intravenous sedation 18,19) .…”