Sesquiterpene and monoterpene derivatives from the soil-derived fungus Trichoderma reesei PSU-SPSF013

Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346

“…Trichocitrinovirene A ( 1 ) was isolated as a colorless gum and had the molecular formula C 15 H 22 O 5 on the basis of the HRESIMS peak at m / z 305.1359 [M + Na] + . The IR spectrum exhibited absorption bands at 3336, 1684, and 1649 cm −1 for hydroxy, conjugated carboxyl carbonyl, and double bond functional groups, respectively [ 10 ]. The 1 H NMR spectrum ( Table 1 ) displayed characteristic signals for two olefinic protons of two trisubstituted alkenes (δ H 6.64, d, J = 10.5 Hz, and 5.31, s, each 1H), two methine protons (δ H 3.06 and 1.35, each m, 1H), one set of equivalent oxymethylene protons (δ H 3.92, s, 2H), three sets of nonequivalent methylene protons (δ H 3.40 and 3.30, each d, J = 16.8 Hz, 1H; δ H 2.13 and 2.04, each m, 1H; δ H 1.81 and 1.39, each m, 1H), and an isopropyl group (δ H 1.71, m, 1H, and δ H 0.95 and 0.82, each d, J = 6.9 Hz, 3H).…”

“…virens [ 11 – 12 ], T . reesei [ 10 ], and Xylaria sp. [ 8 , 13 ] whereas compound 7 was obtained from Fusidium sp.…”

The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade

“…Moreover, only 115 was active against C. neoformans ATCC90112 with the MIC value of 32 μg/mL. 55 Compounds 295 – 297 also displayed moderate inhibitory effects on MR Staphylococcus aureus, Staphylococcus aureus and Bacillus subtilis , which could be the major anti-bacterial constituents of Cephalotrichum microsporum . 104 Tolypocladin K 149 displayed moderate antifungal activity against Sclerotinia sclerotiorun, Helminthosporium maydis, Botrytis cinereal Pers.…”

“… 38 Three new sesquiterpenes Trichodermapenes A-C 113 – 115 ( Figure 3A ) were isolated from the soil-derived fungus Trichoderma reesei PSU-SPSF013. 55 Chemical investigation of the Dictyosporium digitatum fungus resulted in the identification of three undescribed compounds 116 – 118 ( Figure 3A ). which were named Dictyosporin A 116 , Dictyosporin B 117 , Dictyosporin C 118 respectively.…”

“…One new monoterpene named Trichodermanene 151 ( Figure 3C ) was isolated from the soil-derived fungus Trichoderma reesei PSU-SPSF013. 55 Three new meroterpenoid derivatives, 4.25-dehydrominiolutelide B 152 ( Figure 3C ), 4 ,25-dehydro-22- deoxyminiolutelide B 153 and isominiolutelide A 154 ( Figure 3C ), were isolated from the shaken culture of the fungus Penicillium sp. MA-37.…”