Introduction: We encountered variation in the placement of large intestine in abdominal cavity of a 76-years-old male cadaver during dissection of abdominal cavity. The work was performed in Department of Anatomy during routine MBBS teaching sessions. The aim of this paper is to report coexistence of error of mid-gut development and along with variant topo-morphology of sigmoid colon in the same cadaver. Case Report: Sub-hepatic caecum with high riding vermiform appendix with absent ascending colon was seen on the right side of abdominal cavity. Concomitantly on the left side of the abdominal cavity dilated, looped sigmoid colon occupied the left hypochondrium, left lumbar region and left iliac fossa. We report these findings along with the embryological basis and clinical significance. Conclusion: An insight about the errors in development of mid-gut resulting into the variant topography of caecum will facilitate surgeons and radiologists in prompt diagnosis and quick modification of the protocol during invasive procedures.