This review covers the research and development of use of a comprehensive curricular model of instruction and whether this model can be used to increase educator repertoires in instructing students with ASD. Specific focus was on the use of a blended model of autismspecific preparation and professional development in regard to increasing educator knowledge, educator selfefficacy, and use and application of instructional methods, strategies, and learning supports with students with ASD. The findings suggest that when the goals of autism-specific preparation and professional development are to specifically increase educator repertoires in knowledge of autism and educational treatments, selfefficacy and frequency of use of instructional methods, strategies, and learning supports with students with ASD, the blended curricular model of professional development for teaching students with ASD may be effective.