Many cyber-physical systems face the challenge of appropriately integrating domain-specific human expert knowledge into the cyber part to create a shared sphere of knowledge and intelligent interactions between humans and the semi-autonomous technical system. Cognitive engineering contributes methods and insights into higher-order cognition that help to embed human knowledge in an appropriate way. The original research introduces a novel transdisciplinary framework called Human-CoMo, which demonstrates a systematic modelling process, different human perspectives, and the integration of expert knowledge at multiple hierarchical levels. Fundamental principles inspired by human cognition, such as conceptual chunking and knowledge precision, are characterised. Furthermore, it is shown how knowledge hierarchies can be methodically reflected in appropriate data analysis and modelling levels for small and big data applications including artificial intelligence approaches. Combined knowledge- and data-based modelling approaches offer more flexibility to integrate the strengths of humans and technology in a complementary way. The cognitive foundations and their computational reflections are outlined for the technical example process electroplating from the field of materials and surface engineering. The possibilities and limitations of integrating human knowledge through formalisation and implications for future forms of human-machine interaction are discussed.