Setting the agenda for multiple sclerosis rehabilitation research

Kraft, George H.; Johnson, Kurt; Yorkston, Kathryn M.; Amtmann, Dagmar; Bamer, Alyssa M.; Bombardier, Charles H.; Ehde, Dawn M.; Fraser, Robert; Starks, Helene

doi:10.1177/1352458508093891

Cited by 22 publications

(18 citation statements)

References 45 publications

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“…Studies report that perceived neurocognitive functioning is indeed more strongly associated with depression than with objective neuropsychological findings (Benedict et al, 2008; Julian, Merluzzi, & Mohr, 2007a). However, people with MS often report a large number of symptoms concurrently, some of the most common being: fatigue, pain, depression, anxiety, and sleep disturbance (Kraft et al, 2008). Recent research, both within and outside of MS, suggests that depression is not the only predictor of perceived cognitive impairment.…”

Section: Introductionmentioning

confidence: 99%

Beyond depression: Predictors of self-reported cognitive function in adults living with MS.

Beier¹,

Amtmann²,

Ehde³

2015

Rehabilitation Psychology

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Objective To investigate the association between self-reported cognition and demographic/psychosocial variables in individuals with a self-reported diagnosis of multiple sclerosis (MS). Design Secondary longitudinal analysis of mailed self-report surveys over a period of 2 years. Setting Community. Participants 407 community-dwelling individuals from the Pacific Northwest with a self-reported diagnosis of MS. Interventions Not applicable. Main Outcome Measures Subjective general cognitive concerns and subjective executive difficulties as measured by the Neuro-QOL Applied Cognition–Executive Function–Short Form (SF) and the Applied Cognition–General Concerns–SF. Results Univariate and multiple linear regression analyses were used to identify statistically significant longitudinal predictors of perceived cognitive difficulties 2 years later. Fatigue and anxiety were statistically significant predictors of general cognitive concerns. Fatigue and perceived stress were statistically significant predictors of perceived executive difficulties. Fatigue was the strongest predictor in both models. Conclusions In MS, perceived cognitive impairment is frequently linked to depression without consideration of other possible contributors. This study suggests that in people with MS, fatigue is a stronger predictor of self-reported cognitive function two years later than depression

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Section: Introductionmentioning

confidence: 99%

Beyond depression: Predictors of self-reported cognitive function in adults living with MS.

Beier¹,

Amtmann²,

Ehde³

2015

Rehabilitation Psychology

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“…Pain, fatigue, depression, and cognitive impairment often co-occur, and the effect of all may be greater than the sum of each individually (eg, depression can worsen fatigue and cognitive impairment can worsen depression). [6][7][8] Consideration of the co-occurrence of secondary conditions in the context of overall disease symptoms and burden is thought to be critical for successful assessment and clinical intervention in MS. 9 Although rehabilitation and psychological treatments exist for individually addressing many of the specific conditions associated with MS, interventions typically do not focus on how to manage the constellation of symptoms. While it is known that people with MS and other chronic conditions develop coping techniques discussion can help to identify areas of agreement and disagreement.…”

mentioning

confidence: 99%

Perspectives on Self-Management in Multiple Sclerosis

Knaster¹,

Yorkston²,

Johnson³

et al. 2011

International Journal of MS Care

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The aim of this study was to elucidate the experience of self-management among people with multiple sclerosis (MS) and gather their input to inform a self-management intervention. Twelve people with MS participated in focus groups in which they were asked open-ended questions about MS symptoms, challenges, overcoming challenges, symptom management, and treatment preferences. The results suggest four major themes: 1) "The Everyday Experience of MS," including comments about symptoms and their impact on functioning; 2) "Motivation for Self-Management," including descriptions of motivation originating from physical necessity, success with other management techniques, and external sources; 3) "Coping Strategies and Skills," including descriptions of changing behaviors, expanding social support networks, finding resources, utilizing medical treatment, and monitoring symptoms; and 4) "Vision for a Self-Management Intervention," including suggestions that an intervention be individualized, be motivating, and provide resources. The results of this study can inform the design and implementation of self-management interventions. Experiences described by participants are consistent with other qualitative reports suggesting the active role people with MS play in managing their condition. Intervention approaches must consider the complex constellation of symptoms associated with MS and provide individualized treatments that enhance the person's ability to manage their symptoms, barriers presented by such symptoms, and their health care. Int J MS Care. 2011;13:146-152.

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“…In Solari et al study, physical rehabilitation determined improvement in disability detected by FIM motor domains and had a positive impact on mental components of HRQoL perception [25]. Kraft et al performed a stratified, randomised, waitlist controlled study over 12 months, in which an individualised rehabilitation programme reduced disability as measured by FIM motor domains, while there were no differences between control and treatment group as regard to participation and QoL [12].…”

Section: Jmir Serious Games [33]mentioning

confidence: 99%

“…Within these programmes, rehabilitation can be highly useful in person with MS (PwMS). While immunomodulating drugs aim to decrease exacerbations and slow down disease progression, rehabilitative intervention has mainly different goals, which can be shortly summarised: a) improving or maintaining general health; b) mitigating impairment of function such as loss of strength; c) minimising the effects of impairment such as spasticity; d) providing adaptive strategies to minimise disability; e) providing adaptive equipment and devices, such as orthoses, canes and wheelchairs, in order to reduce functional dependence; f) training skills to improve vocational capabilities; g) giving counselling to enhance strategies of coping with the changes brought on by the disease; h) providing symptomatic management [10][11][12]. All these aims should be included within a multidisciplinary rehabilitation project.…”

Section: Introductionmentioning

confidence: 99%