Settling properties of venous blood demonstrated in the peripheral vasculature using susceptibility‐weighted imaging (SWI)

Barnes, Samuel; Haacke, E. Mark

doi:10.1002/jmri.21791

Cited by 7 publications

(5 citation statements)

References 24 publications

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“…21 Such samples may paradoxically not cause a marked signal void in SWI either. This is in contrast with the findings of Barnes and associates 44 who have shown that in vivo blood sedimentation because of stasis in veins is related to phase shift and signal decrease in SWI.…”

Section: Discussioncontrasting

confidence: 99%

Cerebral Microbleeds Temporarily Become Less Visible or Invisible in Acute Susceptibility Weighted Magnetic Resonance Imaging: A Rat Study

Tóth

Berente

Bogner

et al. 2019

Journal of Neurotrauma

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Previously, we reported human traumatic brain injury cases demonstrating acute to subacute microbleed appearance changes in susceptibility-weighted imaging (SWI—magnetic resonance imaging [MRI]). This study aims to confirm and characterize such temporal microbleed appearance alterations in an experimental model. To elicit microbleed formation, brains of male Sprague Dawley rats were pierced in a depth of 4 mm, in a parasagittal position bilaterally using 159 μm and 474 μm needles, without the injection of autologous blood or any agent. Rats underwent 4.7 T MRI immediately, then at multiple time points until 125 h. Volumes of hypointensities consistent with microbleeds in SWI were measured using an intensity threshold-based approach. Microbleed volumes across time points were compared using repeated measures analysis of variance. Microbleeds were assessed by Prussian blue histology at different time points. Hypointensity volumes referring to microbleeds were significantly decreased (corrected p < 0.05) at 24 h compared with the immediate or the 125 h time points. By visual inspection, microbleeds were similarly detectable at the immediate and 125 h imaging but were decreased in extent or completely absent at 24 h or 48 h. Histology confirmed the presence of microbleeds at all time points and in all animals. This study confirmed a general temporary reduction in visibility of microbleeds in the acute phase in SWI. Such short-term appearance dynamics of microbleeds should be considered when using SWI as a diagnostic tool for microbleeds in traumatic brain injury and various diseases.

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Section: Discussioncontrasting

confidence: 99%

Cerebral Microbleeds Temporarily Become Less Visible or Invisible in Acute Susceptibility Weighted Magnetic Resonance Imaging: A Rat Study

Tóth

Berente

Bogner

et al. 2019

Journal of Neurotrauma

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“…IPH is usually defined as a two‐fold hyperintense signal within the carotid wall compared with adjacent sternocleidomastoid muscle. Normal vessel walls and calcification are diamagnetic , whereas IPH is paramagnetic. This leads to opposite phase polarities, which could be utilized in SWI and QSM for better differentiation of calcification from IPH .…”

Section: Clinical Applications Of Swimentioning

confidence: 99%

Susceptibility‐weighted imaging: current status and future directions

Liu¹,

Buch²,

et al. 2016

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Susceptibility weighted imaging (SWI) is a method that uses the intrinsic nature of local magnetic fields to enhance image contrast in order to improve the visibility of various susceptibility sources and to facilitate the diagnostic interpretation. It is also the precursor to the concept of using phase for quantitative susceptibility mapping (QSM). Nowadays, SWI has become a widely used clinical tool to image deoxyhemoglobin in veins, iron deposition in the brain, hemorrhages, microbleeds, and calcification. In this paper, we review the basics of SWI, including data acquisition, data reconstruction and post-processing. In particular, the source of cusp artifacts in phase images is investigated in detail and an improved multi-channel phase data combination algorithm is provided. In addition, we show a few clinical applications of SWI for imaging stroke, traumatic brain injury, carotid vessel wall, siderotic nodules in cirrhotic liver, prostate cancer, prostatic calcification, spinal cord injury and intervertebral disc degeneration. As the clinical applications of SWI continue to expand both in and outside the brain, improving SWI in conjunction with QSM is an important future direction of this technology.

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“…Although this technique is in constant development, it has several clinical applications including the detection of trauma associated hemorrhages, strokes, brain tumors, neurodegenerative diseases and Sturge-Weber syndrome [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

The influence of the blood pressure on the venous cerebral flow measured by magnetic susceptibility (SWI) technique

Martins¹,

Carreiras²,

Ribeiro³

et al. 2013

JBiSE

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Susceptibility Weighted Image (SWI) is a Magnetic Resonance Imaging (MRI) technique that combines high spatial resolution and sensitivity to magnetic susceptibility differences between tissues, it is extremely sensitive to venous blood due to its iron content of deoxyhemoglobin. The aim of this study was to evaluate the differences in the cerebral venous vasculature produced by the value’s variation of blood pressure. 20 subjects (10 hypertensive and 10 normotensive patients) underwent a MRI system with field strength of 1.5 T using a synergy head coil (7 channels). The obtained sequences were T1w, T2w-FLAIR, T2* and SWI. The value of Contrast-to-Noise Ratio (CNR) was assessed in MinIP (Minimum Intensity Projection) and Magnitude images, through drawing free hand ROIs in venous structures: Superior Sagittal Sinus (SSS) Internal Cerebral Vein (ICV) and Sinus Confluence (SC). The obtained values were presented in descriptive statistics-quartiles and extremes diagrams. The results were compared between groups. CNR shown higher values for normotensive group in MinIP (108.89 ± 6.907) to ICV; (238.73 ± 18.556) to SC and (239.384 ± 52.303) to SSS. These values are bigger than images from Hypertensive group about 46 au in average. Comparing the results of Magnitude and MinIP images, there were obtained lower CNR values for the hypertensive group. There were differences in the CNR values between both groups, being these values more expressive in the large vessels-SSS and SC. The SWI is a potential technique to evaluate and characterize the blood pressure variation in the studied vessels adding a physiological perspective to MRI and giving a new approach to the radiological vascular studies.

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Settling properties of venous blood demonstrated in the peripheral vasculature using susceptibility‐weighted imaging (SWI)

Cited by 7 publications

References 24 publications

Cerebral Microbleeds Temporarily Become Less Visible or Invisible in Acute Susceptibility Weighted Magnetic Resonance Imaging: A Rat Study

Cerebral Microbleeds Temporarily Become Less Visible or Invisible in Acute Susceptibility Weighted Magnetic Resonance Imaging: A Rat Study

Susceptibility‐weighted imaging: current status and future directions

The influence of the blood pressure on the venous cerebral flow measured by magnetic susceptibility (SWI) technique

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