Seventeen-year-old girl hospitalized for localized swelling, pruritus, tenderness, and lymphatic streaking with eosinophilia

Kennedy, Joshua L.; Jeffus, Susanne K.; Platts-Mills, Thomas A.E.; Tripathi, Anju; Divjan, Adnan; Perzanowski, Matthew S.; Heymann, Peter W.

doi:10.1016/j.jaip.2013.01.008

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…Patients with higher eosinophil percentages in the blood were more likely to be infested with bed bugs. Eosinophilia has been reported previously in a small number of case reports, and it has been observed in skin biopsies from patients with bed bugs [26,27,28,29]. Similarly, mice that were fed on by bed bugs had higher eosinophil, basophil, and monocyte counts [30], and eosinophilia have been reported with Pediculus humanus capitis (head lice) and Pediculus humanus corporis (body lice) infestations, consistent with our findings [31].…”

Section: Discussionsupporting

confidence: 91%

Investigating the association of bed bugs with infectious diseases: A retrospective case-control study

Sheele

Libertin

Pritt

et al. 2021

Heliyon

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Bed bugs are common urban pests. Unlike many other blood-feeding human ectoparasites, bed bugs are not known to be vectors of human infectious diseases, but clinical and epidemiological studies to directly interrogate this link have been limited. Here, we aimed to determine whether bed bugs were associated with infectious diseases in a set of infested patients presenting to emergency departments (ED) in the greater Cleveland, OH area. We performed a retrospective case-control study involving 332 ED patients with bed bugs and 4,952 control patients, seen from February 1, 2011, through February 1, 2017. Cases and controls were matched by age, sex, and the presenting ED. Additionally, data were adjusted for !20 sociodemographic variables, triage data, and comorbidities in multivariable regression analyses. Seventeen laboratory values, ten different ED and inpatient diagnoses, chest radiographs, infectious disease consults, and blood cultures were examined. The odds of bed bug infestation were significantly higher for patients that had positive blood cultures, had blood cultures growing coagulase-negative Staphylococcus, were diagnosed with pneumonia, were diagnosed with cellulitis, received an infectious disease consult, received a chest radiograph, and had higher percentages of eosinophils in the blood (P < .05 for all). Additional investigations are needed to determine whether bed bugs directly contribute to disease by transmitting causative agents, whether bed bug exposure contributes secondarily contributes to infections, or whether these associations are better explained by other environmental and social determinants of health.

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Section: Discussionsupporting

confidence: 91%

Investigating the association of bed bugs with infectious diseases: A retrospective case-control study

Sheele

Libertin

Pritt

et al. 2021

Heliyon

View full text Add to dashboard Cite

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Disorders of the Lymphatic Vessels

Mortimer

Gordon

2016

Rook's Textbook of Dermatology, Ninth Edition

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Lymphatic dysfunction interferes with fluid homeostasis, tissue immunity and peripheral fat mobilization. Any chronic oedema represents lymphatic failure. If impaired lymph drainage is solely responsible, then lymphoedema results. This produces characteristic skin changes known as elephantiasis as well as increased fat deposition in the subcutaneous tissues. Impaired immune cell trafficking results in an increased risk of infection, particularly cellulitis/erysipelas, which often becomes recurrent. This chapter describes the clinical consequences of lymphatic dysfunction and in particular the impact on the skin and subcutaneous tissues. The sections are divided according to common clinical presentations.

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Seventeen-year-old girl hospitalized for localized swelling, pruritus, tenderness, and lymphatic streaking with eosinophilia

Cited by 2 publications

References 11 publications

Investigating the association of bed bugs with infectious diseases: A retrospective case-control study

Investigating the association of bed bugs with infectious diseases: A retrospective case-control study

Disorders of the Lymphatic Vessels

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